SPECC1L and ELOA

Data Source:
BioGRID (two hybrid)

		SPECC1L	ELOA
Description		sperm antigen with calponin homology and coiled-coil domains 1 like	elongin A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Spindle Gap Junction Actin Cytoskeleton Filamentous Actin	Extracellular Space Nucleoplasm Elongin Complex Site Of DNA Damage
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Cell Cycle Cell Adhesion Actin Cytoskeleton Organization Cell Division	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter
Pathways			Formation of RNA Pol II elongation complex Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Acne (severe) ( 24927181 30542056) Coronary artery disease ( 32469254 29212778) Mean reticulocyte volume ( 32888494) Severity of nausea and vomiting of pregnancy ( 29563502)
Interacting Genes		11 interacting genes: APC ECPAS EFCAB3 ELOA GLIS2 PPP1R12C SNW1 UBC UBE2I ZFHX3 ZNF250	56 interacting genes: AXIN2 BACH2 BRCA1 CBY2 CCDC57 CDR2L CEP57L1 CEP70 CNTROB CUL5 ELOB ERCC6 EVI5 FAM9B FCHO1 FXR1 GMCL1 GOLGA6A GRIPAP1 HIVEP1 HOMEZ JAKMIP2 KANK2 KLHL2 KRT40 KRTAP10-3 KXD1 LMNA LZTS1 MCC MDFI MED21 MID1 MID2 NAB2 NACC1 NAF1 NFKBID NINL PER2 PLK4 POLR2A PPFIA1 PRDM6 PRMT5 RABEP1 RAD54B RAP1A REXO1 SIRPA SPECC1L TNIP1 TP53BP2 TRIM37 TRIM54 ZNF792
Entrez ID		23384	6924
HPRD ID		11080	02873
Ensembl ID		ENSG00000100014	ENSG00000011007
Uniprot IDs		B2RMV2 Q69YQ0	Q14241
PDB IDs			4HFX
Enriched GO Terms of Interacting Partners?
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