ANKS1A and KCTD9

Data Source:
BioGRID (two hybrid)

		ANKS1A	KCTD9
Description		ankyrin repeat and sterile alpha motif domain containing 1A	potassium channel tetramerization domain containing 9
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Neuron Projection
	Molecular Function	Protein Binding Ephrin Receptor Binding	Protein Binding Identical Protein Binding Protein Self-association Cullin Family Protein Binding
	Biological Process	Substrate-dependent Cell Migration Neuron Remodeling Ephrin Receptor Signaling Pathway Regulation Of Ephrin Receptor Signaling Pathway	Protein Ubiquitination Intracellular Signal Transduction Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 24262325) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary heart disease ( 21378990) Height ( 28552196 23563607 18391951) Mean platelet volume ( 32888494) Non-small cell lung cancer ( 23144319) Obesity-related traits ( 23251661) Platelet distribution width ( 32888494) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for body mass index ( 25673412)	Lymphocyte counts ( 32888494) Monocyte count ( 32888494)
Interacting Genes		99 interacting genes: ABI2 ADGRL1 ALDOC ANKRD55 ARAP3 ARHGAP10 BCAR1 BLZF1 C17orf50 C19orf54 C22orf39 C3orf36 C9orf152 CADPS CCDC184 CCDC33 CHCHD3 CYSRT1 DAB2IP DOK3 EGFR ERBB2 ERBB4 ESM1 FAM217B FAM221A FAM86C1P FCHSD2 FHL5 GOLGA2 GPRIN2 HOXA1 HOXC8 ID3 IKZF3 ISCA2 ITIH6 KCTD9 KEAP1 KIAA1328 KLF15 KLHL26 KPRP KRT31 KRT34 KRT39 KRT75 KRT83 KRTAP10-11 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP19-7 KRTAP4-2 KRTAP6-2 KRTAP9-3 LASP1 LHX2 LNX1 MBD3L1 MED20 MEOX2 MID2 MTUS2 NADSYN1 NBPF19 NEDD9 NHLRC2 NOTCH2NLA NUTM2F PIK3R3 PRDM6 PRKAR1B RANBP3 RB1 RIN1 RNF144B RORB RUSC1 SCN5A SH3KBP1 SHISA6 SLC15A2 SMARCD1 SORBS3 SPATA12 SPRED1 TOX2 TP53BP1 TRIM29 TRIT1 UBC USP54 USP7 YWHAG ZBTB32 ZBTB42 ZC2HC1C ZNF135	94 interacting genes: ADAMTSL4 ANKS1A AQP1 ARID5A BANP BLZF1 C19orf54 C7orf31 C9orf24 CARD9 CBX8 CCDC33 CDC37 CDPF1 CFP CRADD CUL3 DDIT4L DEUP1 EHHADH EPM2AIP1 FAM124B GEM GOLGA6A GOLGA6L9 GORASP2 GPANK1 HOXA1 HOXC8 IGFN1 IL16 INCA1 KIF9 KLHL26 KRT31 KRT34 KRT35 KRT40 KRTAP13-2 KRTAP13-3 LNX1 LONRF1 MAD2L2 MBD3L1 MEOX2 MIIP MVP NDUFAB1 NIF3L1 NTAQ1 NUP35 PDZD4 PFDN5 PICK1 PLOD3 PNKD POF1B PPP1R16B PPP1R18 PPP1R32 PRDM6 PRKAA2 PSMA1 PSMB2 RBPMS RFX6 RUSC1 SDCBP SKP1 SLAIN1 SMARCB1 SMUG1 SPATS1 SPG21 STX11 SYT6 TASOR2 TEPSIN TEX37 TNS2 TRIM27 TRIM32 TRIM42 TRIP6 UNKL USP21 USP54 WDR83 ZBTB25 ZBTB42 ZNF408 ZNF426 ZNF620 ZNF76
Entrez ID		23294	54793
HPRD ID		10610	13772
Ensembl ID		ENSG00000064999	ENSG00000104756
Uniprot IDs		Q05CP0 Q92625	Q7L273
PDB IDs		2LMR 2MYQ 6F7O	5BXH
Enriched GO Terms of Interacting Partners?
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