KLHL18 and SCAP

Data Source:
BioGRID (affinity chromatography technology)

		KLHL18	SCAP
Description		kelch like family member 18	SREBF chaperone
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Protein-containing Complex
	Molecular Function	Protein Binding	Protein Binding Sterol Binding Protein-containing Complex Binding Unfolded Protein Binding
	Biological Process	Cell Cycle Protein Ubiquitination Cell Division Positive Regulation Of Mitotic Cell Cycle Phase Transition	Response To Hypoxia Immune Response Aging Cholesterol Metabolic Process Response To Insulin SREBP Signaling Pathway Regulation Of Fatty Acid Biosynthetic Process Cellular Lipid Metabolic Process Negative Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Cholesterol Biosynthetic Process COPII-coated Vesicle Cargo Loading
Pathways			Regulation of cholesterol biosynthesis by SREBP (SREBF) Regulation of cholesterol biosynthesis by SREBP (SREBF)
Drugs
Diseases
GWAS		Huntington's disease progression ( 28642124) Refractive error ( 32231278)	Refractive error ( 32231278) Triglyceride levels ( 32203549)
Interacting Genes		2 interacting genes: AURKA EEF1G	5 interacting genes: INSIG1 INSIG2 PGRMC1 SEC24B SREBF2
Entrez ID		23276	22937
HPRD ID		10017	03300
Ensembl ID		ENSG00000114648	ENSG00000114650
Uniprot IDs		A0A024R2T4 B4DHW4 O94889	B7Z6H0 Q12770
PDB IDs
Enriched GO Terms of Interacting Partners?
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