PLEKHM2 and KLC1

Data Source:
HPRD (in vitro)

		PLEKHM2	KLC1
Description		pleckstrin homology and RUN domain containing M2	kinesin light chain 1
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GO Annotations	Cellular Component	Endosome Membrane	Cytosol Kinesin Complex Microtubule Membrane Growth Cone Cytoplasmic Vesicle
	Molecular Function	Protein Binding Kinesin Binding	Motor Activity Protein Binding
	Biological Process	Golgi Organization Lysosome Localization Regulation Of Protein Localization Positive Regulation Of Membrane Tubulation	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Stress Granule Disassembly
Pathways			MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Estimated glomerular filtration rate ( 31015462)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 28892062 25673413) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Schizophrenia ( 25056061) Smoking behaviour (cigarette pack-years) ( 30679032) Urate levels ( 31578528)
Interacting Genes		2 interacting genes: KLC1 SLC39A1	28 interacting genes: ADRB2 AP1AR APP ATCAY BNIP2 CLSTN1 ERBB2 F2RL1 HSPB1 KIF2A KIF5C KLC2 KRT31 LRSAM1 MAPK6 MAPK8IP1 MAPK8IP2 MAPK8IP3 NIN ODAD1 ODF1 PCM1 PLEKHM2 PTGER4 SNCA SPAG9 TACC3 YWHAB
Entrez ID		23207	3831
HPRD ID		11440	02489
Ensembl ID		ENSG00000116786	ENSG00000126214
Uniprot IDs		Q5VVD7 Q8IWE5	Q07866 Q7RTQ2
PDB IDs		3CXB 3HW2 3ZFW	3NF1 5OJ8
Enriched GO Terms of Interacting Partners?
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