ARL6IP1 and SNX10

Data Source:
BioGRID (two hybrid)

		ARL6IP1	SNX10
Description		ADP ribosylation factor like GTPase 6 interacting protein 1	sorting nexin 10
Image		No pdb structure
GO Annotations	Cellular Component	Sec61 Translocon Complex Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane	Nucleus Endoplasmic Reticulum Centrosome Secretory Granule Extrinsic Component Of Endosome Membrane Apical Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding 1-phosphatidylinositol Binding ATPase Binding
	Biological Process	Positive Regulation Of L-glutamate Import Across Plasma Membrane Cotranslational Protein Targeting To Membrane Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Endoplasmic Reticulum Tubular Network Formation Regulation Of Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Membrane Organization	Gastric Acid Secretion Intracellular Protein Transport Endocytosis Endosome Organization Osteoclast Differentiation Bone Mineralization Involved In Bone Maturation Tooth Eruption Bone Resorption Calcium Ion Homeostasis Cilium Assembly Protein Localization To Cilium Protein Localization To Centrosome Ruffle Assembly Cellular Response To Leukemia Inhibitory Factor
Pathways
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Dental caries (decayed, missing and filled teeth) ( 31533690) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Mean reticulocyte volume ( 32888494) Metabolic syndrome ( 31589552) Metabolite levels ( 23823483) Triglyceride levels ( 32203549) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes		77 interacting genes: ACSF2 AQP6 ARL4D ARL6 C19orf18 CERT1 DIABLO EHD3 EMP1 F2RL1 FBXW7 FDFT1 FXR2 GAD2 GAS8 GOLPH3 GOLPH3L GORASP2 GPR151 GPR152 HGS HMGCL HSD17B13 INPP5K LMNA MCEMP1 MFSD14B MFSD5 MGST3 MIEF2 MTERF3 MYG1 NAPB NDRG4 NTAQ1 NUDT3 PAM16 PBX3 PICK1 PTPN9 RAB33A REEP6 RETREG3 RNF5 SDCBP SENP2 SHISA5 SHMT2 SLC10A6 SLC13A1 SLC35C2 SNX1 SNX10 SNX11 SNX12 SNX15 SNX2 SNX3 SNX4 SNX8 SPG21 STARD4 SUCLA2 TARS2 TFAM TMED8 TMEM14B TMEM248 TMEM258 TUFM UBE2I VMA21 WDFY2 WIPI2 YIPF4 ZFYVE21 ZNF391	3 interacting genes: ARL6IP1 RABAC1 YIF1A
Entrez ID		23204	29887
HPRD ID		09641	15409
Ensembl ID		ENSG00000170540	ENSG00000086300
Uniprot IDs		A0A024QYV7 Q15041	A0A024RA70 B4DJM0 Q8N5Z3 Q9Y5X0
PDB IDs			4ON3 4PZG
Enriched GO Terms of Interacting Partners?
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