NFASC and CNTNAP1

Data Source:
HPRD (in vitro)

		NFASC	CNTNAP1
Description		neurofascin	contactin associated protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Dendrite Paranodal Junction Node Of Ranvier Axon Initial Segment Schwann Cell Microvillus Ficolin-1-rich Granule Membrane	Integral Component Of Plasma Membrane Integral Component Of Membrane Paranodal Junction Paranode Region Of Axon Presynaptic Active Zone Membrane
	Molecular Function	Protein Binding Protein Domain Specific Binding	Protein Binding SH3 Domain Binding Signaling Receptor Activity
	Biological Process	Cell Adhesion Axon Guidance Peripheral Nervous System Development Transmission Of Nerve Impulse Myelination Neutrophil Degranulation Synapse Organization Protein Localization To Plasma Membrane	Protein Localization To Paranode Region Of Axon Cytoskeleton Organization Cell Adhesion Signal Transduction Neuronal Action Potential Propagation Central Nervous System Myelination Myelination In Peripheral Nervous System Paranodal Junction Assembly Neuron Projection Morphogenesis Neuromuscular Process Controlling Posture Neuromuscular Process Controlling Balance Protein Localization To Juxtaparanode Region Of Axon
Pathways		Interaction between L1 and Ankyrins Neurofascin interactions Neurofascin interactions Neutrophil degranulation	Neurofascin interactions
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Blood protein levels ( 30072576 29875488 28240269) Clozapine-induced agranulocytosis ( 25187353) Dental caries ( 23064961) Diisocyanate-induced asthma ( 25918132) Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) ( 30120083) General risk tolerance (MTAG) ( 30643258) High myopia ( 32428537) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494) Regular attendance at a religious group ( 29970889)	Breast cancer ( 29059683) Major depressive disorder ( 27777418)
Interacting Genes		12 interacting genes: ABI1 ABI2 ANK1 CNTNAP1 DCX NRCAM SCN1B SCN3B SCNN1B SDCBP SDCBP2 TNR	7 interacting genes: CCR4 FYN NFASC PTPRB RHOA RTN4 SRC
Entrez ID		23114	8506
HPRD ID		12372	03825
Ensembl ID		ENSG00000163531	ENSG00000108797
Uniprot IDs		B4DRH7 O94856	P78357
PDB IDs		3P3Y 3P40
Enriched GO Terms of Interacting Partners?
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