MYCBP2 and CDC14B

Data Source:
BioGRID (affinity chromatography technology)

		MYCBP2	CDC14B
Description		MYC binding protein 2	cell division cycle 14B
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton Membrane Axon Intracellular Membrane-bounded Organelle	Spindle Pole Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome Mitotic Spindle
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Small GTPase Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Localization Circadian Regulation Of Gene Expression Negative Regulation Of Protein Catabolic Process Regulation Of Catalytic Activity Neuromuscular Process Regulation Of Cytoskeleton Organization Regulation Of Axon Guidance	Microtubule Cytoskeleton Organization Mitotic Cell Cycle DNA Repair Protein Dephosphorylation Regulation Of Exit From Mitosis G2 DNA Damage Checkpoint Positive Regulation Of Cytokinesis Peptidyl-tyrosine Dephosphorylation Cilium Assembly Mitotic Cell Cycle Arrest Signal Transduction Involved In G2 DNA Damage Checkpoint Positive Regulation Of Ubiquitin Protein Ligase Activity
Pathways			MAPK6/MAPK4 signaling
Drugs
Diseases
GWAS		Chronotype ( 30696823) Iris heterochromicity ( 30895295) Morning person ( 30696823) Preeclampsia ( 23551011) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)	Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Height ( 31562340) Household income ( 31844048) Intelligence (MTAG) ( 29326435) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912)
Interacting Genes		15 interacting genes: APPL1 ATP13A2 CALM1 ERBB3 FBXO45 MYC NMNAT2 PTPN12 SRPK2 TTN UBE2D2 UBE2D3 UBE2L3 YWHAG YWHAQ	19 interacting genes: BCL10 BUB1 CCND1 CDKN2A DLC1 MCC MFAP1 MLH3 MSH2 MTDH PRKAB2 PSMB1 SIRT2 SKP2 SMAD4 SPANXN2 STK11 TP53 ZNF696
Entrez ID		23077	8555
HPRD ID		10104	04615
Ensembl ID		ENSG00000005810	ENSG00000081377
Uniprot IDs		O75592	O60729
PDB IDs		5O6C 6T7F	1OHC 1OHD 1OHE
Enriched GO Terms of Interacting Partners?
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