SHANK2 and BANF1

Data Source:
BioGRID (two hybrid)

		SHANK2	BANF1
Description		SH3 and multiple ankyrin repeat domains 2	BAF nuclear assembly factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cellular_component Cytosol Neurofilament Plasma Membrane Ionotropic Glutamate Receptor Complex Postsynaptic Density Apical Plasma Membrane Growth Cone Brush Border Membrane Neuron Projection Neuronal Cell Body Dendritic Spine Postsynaptic Membrane Ciliary Membrane	Condensed Chromosome Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding SH3 Domain Binding Synaptic Receptor Adaptor Activity Ionotropic Glutamate Receptor Binding	DNA Binding Protein Binding Protein C-terminus Binding Enzyme Binding Identical Protein Binding Protein Homodimerization Activity Protein N-terminus Binding LEM Domain Binding
	Biological Process	Synapse Assembly Behavior Learning Positive Regulation Of Cell Population Proliferation Adult Behavior Social Behavior Negative Regulation Of Hippo Signaling Brain Morphogenesis Synaptic Growth At Neuromuscular Junction Positive Regulation Of Synaptic Transmission, Glutamatergic Long-term Synaptic Potentiation Long-term Synaptic Depression Dendritic Spine Morphogenesis Positive Regulation Of Dendritic Spine Development Vocalization Behavior Postsynaptic Density Assembly Regulation Of AMPA Receptor Activity Positive Regulation Of Excitatory Postsynaptic Potential	Chromosome Segregation Mitotic Nuclear Envelope Reassembly Response To Virus DNA Integration Chromosome Condensation Negative Regulation Of Viral Genome Replication Nuclear Transport Establishment Of Integrated Proviral Latency
Pathways		Neurexins and neuroligins Neurexins and neuroligins	Integration of provirus 2-LTR circle formation Integration of viral DNA into host genomic DNA Autointegration results in viral DNA circles APOBEC3G mediated resistance to HIV-1 infection Vpr-mediated nuclear import of PICs Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hip circumference ( 28552196) Late-onset Alzheimer's disease ( 27770636) Obesity-related traits ( 23251661) Response to fenofibrate (adiponectin levels) ( 23149075) Urate levels in obese individuals ( 25811787)	Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Serum uric acid levels ( 32514006)
Interacting Genes		19 interacting genes: ADGRB2 ADGRL1 ADGRL2 ARHGAP12 ARHGEF7 BAIAP2 CTTN DLG4 DLGAP1 DLGAP2 DLGAP3 DLGAP4 DNM2 HOMER1 PPP3CA RIPOR3 SHARPIN SLC9A3 SSTR2	5 interacting genes: BANF2 CRX EMD ERBIN TMPO
Entrez ID		22941	8815
HPRD ID		04479	04817
Ensembl ID		ENSG00000162105	ENSG00000175334
Uniprot IDs		A0A590UJ45 A6NHU9 C0SPH0 Q9UPX8	A0A024R5H0 O75531
PDB IDs			1CI4 1QCK 2BZF 2EZX 2EZY 2EZZ 2ODG 6GHD 6RPR 6UNT 6URE 6URJ 6URK 6URL 6URN 6URR 6URZ 6US0 6US1 6US7 6USB 6USD 6USI
Enriched GO Terms of Interacting Partners?
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