KIFAP3 and NUDT21

Data Source:
BioGRID (two hybrid)

		KIFAP3	NUDT21
Description		kinesin associated protein 3	nudix hydrolase 21
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Endoplasmic Reticulum Golgi Apparatus Centrosome Cytosol Spindle Microtubule Cilium Axoneme Microtubule Cytoskeleton Kinesin II Complex Photoreceptor Connecting Cilium Ciliary Transition Zone Ciliary Basal Body Ciliary Tip Periciliary Membrane Compartment	Nucleus Nucleoplasm Cytoplasm Centrosome MRNA Cleavage And Polyadenylation Specificity Factor Complex MRNA Cleavage Factor Complex Nuclear Body Centriolar Satellite Paraspeckles
	Molecular Function	Protein Binding Kinesin Binding Protein Phosphatase Binding Intraciliary Transport Particle B Binding	Chromatin Binding RNA Binding MRNA Binding Protein Binding Hydrolase Activity MRNA 3'-UTR AU-rich Region Binding Identical Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Process Microtubule-based Movement Signal Transduction Negative Regulation Of Cell Population Proliferation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Intraciliary Transport Involved In Cilium Assembly Negative Regulation Of Apoptotic Process Cilium Organization Positive Regulation Of Calcium-dependent Cell-cell Adhesion Protein-containing Complex Assembly Plus-end-directed Vesicle Transport Along Microtubule	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Processing Posttranscriptional Regulation Of Gene Expression Cell Differentiation MRNA 3'-end Processing Positive Regulation Of MRNA Cleavage Protein Tetramerization Protein Heterotetramerization Pre-mRNA Cleavage Required For Polyadenylation MRNA Alternative Polyadenylation Positive Regulation Of MRNA Polyadenylation Messenger Ribonucleoprotein Complex Assembly Positive Regulation Of Stem Cell Differentiation Positive Regulation Of Pro-B Cell Differentiation
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane MHC class II antigen presentation Intraflagellar transport COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins	mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Acute anterior uveitis in ankylosing spondylitis ( 32492107) Adverse response to drug ( 30420678) Amyotrophic lateral sclerosis ( 19451621) Atrial fibrillation ( 28416818) L-selectin levels ( 25576479) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		33 interacting genes: APC AR C19orf44 CCSER2 DHX37 DISC1 GTSE1 HOXB5 KANK2 KIF3B MAP3K10 MAP3K11 MARK2 MEST MINK1 MOS MYPOP NAA10 NAA11 NAV1 NCF2 NIPSNAP3A NUDT21 PARD6G PEX19 PRNP RAP1GDS1 RBFOX1 RBM14 RPGR RTP5 SMC3 SRC	119 interacting genes: A2M ATXN1 CARM1 CDC42 CEP126 CLP1 CPSF6 CPSF7 CTNND2 DBN1 DNMT3L DYNC1I1 EED EEF1G ESR1 EXOSC6 F13A1 FAM90A1 FBN3 FLAD1 FUNDC2 GOLGA2 HSF4 IKZF1 ITCH JMJD1C KIFAP3 KRT75 MASP1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-2 MIR138-1 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200B MIR205 MIR206 MIR20A MIR214 MIR221 MIR25 MIR29A MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-2 MIR9-2 MIR92A1 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MYL6 NEDD4 NGEF NIF3L1 NTAQ1 POLR2C PSMF1 PSPC1 PTN PYCR1 RBM48 RCC1 RNF19A RPLP1 S100PBP SEM1 SEMA5B SF3B1 SHC1 SLC44A1 SNCAIP SNRNP70 SPAG8 SRPK1 TCERG1 TEPSIN TLE1 TRA2A TRIM23 TRIM27 WWOX ZNF655 ZRANB1
Entrez ID		22920	11051
HPRD ID		03499	05400
Ensembl ID		ENSG00000075945	ENSG00000167005
Uniprot IDs		Q92845	A0A024R6W2 O43809
PDB IDs			2CL3 2J8Q 3BAP 3BHO 3MDG 3MDI 3N9U 3P5T 3P6Y 3Q2S 3Q2T 5R4P 5R4Q 5R4R 5R4S 5R4T 5R4U 5R64 5R65 5R66 5R67
Enriched GO Terms of Interacting Partners?
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