KLRK1 and MICB

Data Source:
HPRD (in vitro)

		KLRK1	MICB
Description		killer cell lectin like receptor K1	MHC class I polypeptide-related sequence B
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Integral Component Of Membrane	Extracellular Space Plasma Membrane External Side Of Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Protein Binding Carbohydrate Binding Signaling Receptor Activity	Natural Killer Cell Lectin-like Receptor Binding
	Biological Process	Adaptive Immune Response Signal Transduction Natural Killer Cell Activation Cell Differentiation T Cell Costimulation Negative Regulation Of GTPase Activity Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response Negative Regulation Of Natural Killer Cell Chemotaxis	Adaptive Immune Response Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response Response To Oxidative Stress Response To Heat Viral Process Cytolysis Response To Retinoic Acid Gamma-delta T Cell Activation Negative Regulation Of Defense Response To Virus By Host Regulation Of Immune Response
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell DAP12 interactions DAP12 signaling DAP12 signaling	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Interleukin-1-receptor antagonist levels ( 22205395) Obesity-related traits ( 23251661) Psoriasis ( 28537254)	AIDS progression ( 19115949) Alcohol use disorder ( 30940813) Allergic sensitization ( 23817571) Apolipoprotein B levels ( 32203549) Arterial stiffness index ( 31235810) Asthma ( 31619474 29273806) Asthma (childhood onset) ( 31619474 29273806) Asthma and major depressive disorder ( 31619474) Atopic dermatitis ( 26482879) Autism spectrum disorder or schizophrenia ( 28540026) Behcet's disease ( 23001997) Blood protein levels ( 29875488 28240269) Cervical cancer ( 28806749) Cold sores ( 28928442) Coronary artery disease ( 33020668) Crohn's disease ( 23128233) Cutaneous lupus erythematosus ( 25827949) Dengue shock syndrome ( 22001756) Handedness (non-right-handed vs right-handed) ( 31504236) Hodgkin's lymphoma ( 22286212) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Metabolic syndrome ( 22399527) Midgestational circulating levels of PBDEs ( 28235828) Monocyte count ( 27863252) Mononucleosis ( 28928442) Myositis ( 26291516) Oral cavity cancer ( 27749845) Parental longevity (combined parental attained age, Martingale residuals) ( 29227965) Parental longevity (father's attained age) ( 29227965) Platelet count ( 32888494) Plateletcrit ( 32888494 27863252) Pneumonia ( 28928442) Psychosis (atypical) ( 24132900) Pulmonary function ( 21946350) Refractive error ( 32231278) Rosacea symptom severity ( 29771307) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Triglyceride levels ( 32203549) Ulcerative colitis ( 28067908)
Interacting Genes		8 interacting genes: HCST MICB PDE4C RAE1 RAET1E RAET1G TYROBP ULBP3	2 interacting genes: KLRC4 KLRK1
Entrez ID		22914	4277
HPRD ID		17240	03894
Ensembl ID		ENSG00000213809	ENSG00000204516
Uniprot IDs		A0A024RAP8 P26718	A0A0G2JHB5 A0A7D9H7X8 B4DUT9 B7Z8M1 F5H7Q8 Q29980
PDB IDs		1HYR 1KCG 1MPU 4PDC 4S0U	1JE6 2WY3
Enriched GO Terms of Interacting Partners?
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