DHX30 and DHX58

Data Source:
BioGRID (pull down)

		DHX30	DHX58
Description		DExH-box helicase 30	DExH-box helicase 58
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GO Annotations	Cellular Component	Intracellular Anatomical Structure Cytoplasm Mitochondrion Cytosol Ribonucleoprotein Granule Mitochondrial Nucleoid	Cytoplasm
	Molecular Function	Chromatin Binding RNA Binding RNA Helicase Activity Double-stranded RNA Binding Protein Binding ATP Binding	DNA Binding RNA Helicase Activity Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding ATP Binding Zinc Ion Binding
	Biological Process	Central Nervous System Development Mitochondrial Large Ribosomal Subunit Assembly	Response To Virus Response To Bacterium Viral Process Negative Regulation Of Type I Interferon Production Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Negative Regulation Of MDA-5 Signaling Pathway Negative Regulation Of RIG-I Signaling Pathway Innate Immune Response Regulation Of Innate Immune Response Negative Regulation Of Innate Immune Response Defense Response To Virus Positive Regulation Of MDA-5 Signaling Pathway Positive Regulation Of RIG-I Signaling Pathway
Pathways			DDX58/IFIH1-mediated induction of interferon-alpha/beta
Drugs
Diseases
GWAS			Coronary artery disease ( 29212778) Fasting plasma glucose ( 31932636) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		17 interacting genes: CDK9 DHX58 DUX4 HDAC1 HDAC3 HNRNPD MYBBP1A NCOR1 NEDD4 NR2E3 OAS3 RBBP4 RBBP7 RBL1 SIN3A SKIL TBL3	9 interacting genes: AGO2 AP2B1 APP DHX30 DICER1 EIF2AK2 EIF6 NKRF STAU2
Entrez ID		22907	79132
HPRD ID		13142	13115
Ensembl ID		ENSG00000132153	ENSG00000108771
Uniprot IDs		H7BXY3 Q7L2E3	A0A024R1Y5 Q96C10
PDB IDs		2DB2	2RQA 2W4R 3EQT
Enriched GO Terms of Interacting Partners?
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