BTBD3 and PLXNB3

Data Source:
HPRD (two hybrid)

		BTBD3	PLXNB3
Description		BTB domain containing 3	plexin B3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Semaphorin Receptor Complex Plasma Membrane Integral Component Of Plasma Membrane Cell Surface
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Semaphorin Receptor Activity Protein Domain Specific Binding Rho GDP-dissociation Inhibitor Binding Cell-cell Adhesion Mediator Activity
	Biological Process	Cerebral Cortex Development Neurogenesis Dendrite Morphogenesis	Positive Regulation Of Endothelial Cell Proliferation Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Negative Regulation Of Cell Adhesion Regulation Of Cell Shape Negative Regulation Of Lamellipodium Assembly Positive Regulation Of Neuron Projection Development Regulation Of Cell Migration Negative Regulation Of Cell Migration Negative Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Axonogenesis Positive Chemotaxis Cell Chemotaxis Semaphorin-plexin Signaling Pathway Semaphorin-plexin Signaling Pathway Involved In Axon Guidance
Pathways			Other semaphorin interactions
Drugs
Diseases
GWAS		Benign prostatic hyperplasia ( 30988330) Cardiac hypertrophy ( 21348951) Cognitive decline rate in late mild cognitive impairment ( 26252872) Diastolic blood pressure ( 30224653) Hearing function ( 25060954) Intraocular pressure ( 29785010) Logical memory (delayed recall) in normal cognition ( 29274321) Logical memory (immediate recall) in normal cognition ( 29274321) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Serum metabolite ratios in chronic kidney disease ( 29545352)
Interacting Genes		10 interacting genes: BTBD6 CDC37 CUL3 GORASP2 MEOX2 PLXNB3 RNF4 SUMO1 TEPSIN UBE2I	8 interacting genes: ARHGEF11 BTBD3 CUL7 CUL9 MAGI2 MAGI3 RIT2 SPOCK2
Entrez ID		22903	5365
HPRD ID		12538	02198
Ensembl ID		ENSG00000132640	ENSG00000198753
Uniprot IDs		B4DK27 B4DRI6 Q9Y2F9	A8K920 Q9ULL4
PDB IDs
Enriched GO Terms of Interacting Partners?
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