KHDC4 and PIDD1

Data Source:
BioGRID (two hybrid)

		KHDC4	PIDD1
Description		KH domain containing 4, pre-mRNA splicing factor	p53-induced death domain protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol
	Molecular Function	RNA Binding Protein Binding	Endopeptidase Activity Death Receptor Binding Protein Binding
	Biological Process	MRNA Splice Site Selection	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To DNA Damage Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Protein Autoprocessing Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways			TP53 Regulates Transcription of Caspase Activators and Caspases
Drugs
Diseases
GWAS			Breast cancer ( 29059683)
Interacting Genes		21 interacting genes: BANP C14orf119 DNAJC5 KCNIP3 MAGEA12 NRF1 NUTF2 PIDD1 PRKAB2 PRR13 PSMB1 PUF60 QRICH1 RBM23 RBM39 RHOXF2 SAT1 SPANXN2 U2AF2 ZDHHC17 ZRSR2	15 interacting genes: AFP CASP2 CCDC85B CRADD EFEMP2 FADD HSD17B14 KHDC4 MADD MAFG MDFI MTNR1B POGZ SOX8 TEAD3
Entrez ID		22889	55367
HPRD ID		17198	11284
Ensembl ID		ENSG00000132680	ENSG00000177595
Uniprot IDs		Q7Z7F0	Q9HB75
PDB IDs		2YQR	2OF5
Enriched GO Terms of Interacting Partners?
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