ZNF652 and CBFA2T3

Data Source:
HPRD (in vivo)

		ZNF652	CBFA2T3
Description		zinc finger protein 652	CBFA2/RUNX1 partner transcriptional co-repressor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Golgi Membrane Nucleus Nucleoplasm Nucleolus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Response To Hypoxia Transcription, DNA-templated Negative Regulation Of Cell Population Proliferation Granulocyte Differentiation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Glycolytic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Aerobic Respiration
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 31361310 31959851 30929738 32296059 31619474 29273806) Asthma (adult onset) ( 30929738) Asthma (childhood onset) ( 31036433 30929738) Asthma (moderate or severe) ( 30552067) Atopic dermatitis ( 23727859) Blood pressure ( 21909110) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Cancer ( 29299148) Coronary artery disease ( 29212778) Diastolic blood pressure ( 19430483 27841878 28739976 27618447 27618452) Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Egg allergy (maternal genetic effects) ( 29489655) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Height ( 20881960) Intraocular pressure ( 29785010) Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Mean reticulocyte volume ( 32888494) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252) Prostate cancer ( 23535732 21602798) Refractive error ( 32231278) Sex hormone-binding globulin levels ( 22829776) Systolic blood pressure ( 27841878 27618452) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Thyroid stimulating hormone levels ( 32769997) Triglyceride levels ( 32203549)	Annualised percent change of cerebrospinal fluid AB1-42 levels ( 31370031) Carotid intima media thickness ( 30510157) Carotid intima media thickness (mean) ( 31801372) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Hair color ( 26926045) Hemoglobin levels ( 32327693) Immature fraction of reticulocytes ( 32888494) Levodopa-induced dyskinesia in levodopa treated Parkinson's disease ( 32733355) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Red cell distribution width ( 32888494) Red vs. brown/black hair color ( 30531825) Social autistic-like traits ( 24133439) Vitiligo ( 27723757)
Interacting Genes		4 interacting genes: CBFA2T2 CBFA2T3 RUNX1T1 TRIM14	23 interacting genes: ARHGEF6 CBFA2T2 CHRM4 EPM2AIP1 GAS8 GATAD2A GMEB2 HDAC1 HDAC3 MATN2 PIN1 PRKAR2A RTN4IP1 RUNX1 RUNX1T1 SEC24A TCF3 VPS37C ZBTB33 ZBTB38 ZBTB4 ZBTB47 ZNF652
Entrez ID		22834	863
HPRD ID		18362	04847
Ensembl ID		ENSG00000198740	ENSG00000129993
Uniprot IDs		A8K9F2 Q9Y2D9	O75081
PDB IDs
Enriched GO Terms of Interacting Partners?
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