FKBP1B and RYR3

Data Source:
BioGRID (pull down)

		FKBP1B	RYR3
Description		FKBP prolyl isomerase 1B	ryanodine receptor 3
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GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane Z Disc Sarcoplasmic Reticulum Membrane Calcium Channel Complex	Smooth Endoplasmic Reticulum Plasma Membrane Integral Component Of Membrane Sarcoplasmic Reticulum Z Disc Cytoplasmic Vesicle Membrane Sarcoplasmic Reticulum Membrane Calcium Channel Complex Sarcolemma
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Signaling Receptor Binding Ryanodine-sensitive Calcium-release Channel Activity Protein Binding FK506 Binding Calcium Channel Inhibitor Activity Cyclic Nucleotide Binding Ion Channel Binding	Ryanodine-sensitive Calcium-release Channel Activity Calcium Ion Binding Calmodulin Binding Calcium-release Channel Activity Calcium-induced Calcium Release Activity
	Biological Process	Protein Peptidyl-prolyl Isomerization 'de Novo' Protein Folding Smooth Muscle Contraction Response To Glucose Negative Regulation Of Heart Rate Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Neuronal Action Potential Propagation Protein Maturation By Protein Folding Insulin Secretion Negative Regulation Of Phosphoprotein Phosphatase Activity Response To Vitamin E Ion Transmembrane Transport Calcium-mediated Signaling Using Intracellular Calcium Source Protein Refolding T Cell Proliferation Response To Hydrogen Peroxide Positive Regulation Of Axon Regeneration Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Sequestering Of Calcium Ion Regulation Of Cytosolic Calcium Ion Concentration Response To Redox State Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Chaperone-mediated Protein Folding Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Cardiac Conduction	Calcium Ion Transport Ion Transmembrane Transport Release Of Sequestered Calcium Ion Into Cytosol Protein Homotetramerization Calcium Ion Transmembrane Transport Cellular Response To Calcium Ion Cellular Response To Magnesium Ion Cellular Response To Caffeine Cellular Response To ATP Regulation Of Cardiac Conduction
Pathways		Stimuli-sensing channels Ion homeostasis	Stimuli-sensing channels Ion homeostasis
Drugs
Diseases
GWAS		Chronotype ( 27494321) Quantitative traits ( 19197348)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Carotid atherosclerosis in HIV infection ( 20009918) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Hepcidin/ferritin ratio ( 27846281) Hippocampal volume ( 31530798) Malaria ( 31844061) Periodontitis (Mean PAL) ( 24024966) Schizophrenia ( 30285260) Urinary albumin excretion ( 32277301)
Interacting Genes		12 interacting genes: ADAMTSL4 BMPR1A CAMK2D GMCL1 KRT31 KRT40 KRTAP1-1 REL RYR2 RYR3 TGFBR1 TRIM69	5 interacting genes: BCL2L1 FKBP1A FKBP1B HNF1A RYR2
Entrez ID		2281	6263
HPRD ID		02795	01620
Ensembl ID		ENSG00000119782	ENSG00000198838
Uniprot IDs		F8W6G9 P68106	A0A0U1RRH1 Q15413
PDB IDs		1C9H 4C02 4IQ2 4IQC 5HKG 5L1D 5T15 5T9M 5T9N 5T9R 5T9S 5T9V 5TA3 5TAL 5TAM 5TAN 5TAP 5TAQ 5TAS 5TAT 5TAU 5TAV 5TAW 5TAX 5TAY 5TAZ 5TB0 5TB1 5TB2 5TB3 5TB4 6JGZ 6JH6 6JHN 6JI0 6JI8 6JII 6JIU 6JIY 6JRR 6JRS 6M2W 6PV6 6WOT 6WOU 6WOV 7CF9 7JMF 7JMG 7JMH 7JMI 7JMJ	4ERV 6UHA 6UHB 6UHE 6UHH
Enriched GO Terms of Interacting Partners?
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