CASC3 and ESR2

  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)

CASC3

ESR2

Description CASC3 exon junction complex subunit estrogen receptor 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Atrial fibrillation ( 30061737)
  • Chronotype ( 30696823)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Depression ( 29700475)
  • Hematocrit ( 32888494 27863252)
  • Hemoglobin ( 32888494)
  • Hemoglobin concentration ( 27863252)
  • Hemoglobin levels ( 32327693)
  • Metabolite levels ( 23823483)
  • Prostate cancer ( 26443449)
  • Red blood cell count ( 32888494 27863252)
Interacting Genes 16 interacting genes: AKT1 APC CASP8 CDK6 CDKN2A EIF4A3 ESR2 FGFR4 GRB2 KRTAP6-2 MIR128-1 NBN PHB PTPN1 PTPRJ STAU1 104 interacting genes: AGR3 AKAP13 AKT1 ARID5A BCAS2 CALM1 CALM2 CALM3 CASC3 CASZ1 CCNC CDK8 CYSRT1 DAP3 DDX54 DKK3 DNMT3L DNTTIP2 EP300 ESR1 HOXA1 IL13RA2 IL24 ITIH5 JMJD1C KAT5 KLK9 KPNA3 KPRP KRTAP6-2 LCK LRATD2 MAD2L1 MAPK1 MAPK11 MED1 MED10 MED12 MED14 MED16 MED17 MED20 MED21 MED23 MED24 MED6 MED7 MEOX2 MKNK2 MMS19 MRC2 MSH2 NCOA1 NCOA2 NCOA3 NCOA6 NCOA7 NCOR1 NCOR2 NFKBIB NFKBID NOTCH2NLA NR0B1 NR0B2 NRIP1 OXT PELP1 PIAS1 PIAS2 PIAS3 PLSCR1 PNRC1 PNRC2 PPARGC1A PPP5C PRMT2 PRSS50 PSMC3IP PSMC5 RBFOX2 RBM39 REXO4 RFX6 SERPINH1 SMAD2 SMAD3 SMAD4 SMARCE1 SP1 SRA1 SRC SREBF1 STAT5A TFF1 TRAM1 TRIM24 TRIM59 TRIP4 TXNRD1 WIPI1 YWHAH YWHAQ ZBTB17 ZNHIT3
Entrez ID 22794 2100
HPRD ID 16225 03390
Ensembl ID ENSG00000108349 ENSG00000140009
Uniprot IDs O15234 A0A348FV93 F1D8N3 Q0PTK2 Q7LCB3 Q92731
PDB IDs 2HYI 2J0Q 2J0S 2J0U 2XB2 3EX7 5XJC 5YZG 6ICZ 1L2J 1NDE 1QKM 1U3Q 1U3R 1U3S 1U9E 1X76 1X78 1X7B 1X7J 1YY4 1YYE 1ZAF 2FSZ 2GIU 2I0G 2JJ3 2NV7 2QTU 2YJD 2YLY 2Z4B 3OLL 3OLS 3OMO 3OMP 3OMQ 4J24 4J26 4ZI1 5TOA
Enriched GO Terms of Interacting Partners?
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