ALDOA and GPD2

Data Source:
HPRD (in vitro)

		ALDOA	GPD2
Description		aldolase, fructose-bisphosphate A	glycerol-3-phosphate dehydrogenase 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytosol Actin Cytoskeleton Membrane Platelet Alpha Granule Lumen M Band I Band Secretory Granule Lumen Sperm Head Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Mitochondrion Mitochondrial Inner Membrane Glycerol-3-phosphate Dehydrogenase Complex
	Molecular Function	RNA Binding Actin Binding Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding Tubulin Binding Identical Protein Binding Cadherin Binding Fructose Binding	Glycerol-3-phosphate Dehydrogenase (quinone) Activity Calcium Ion Binding Sn-glycerol-3-phosphate:ubiquinone-8 Oxidoreductase Activity
	Biological Process	Platelet Degranulation Fructose Metabolic Process Gluconeogenesis Glycolytic Process ATP Biosynthetic Process Striated Muscle Contraction Actin Filament Organization Binding Of Sperm To Zona Pellucida Regulation Of Cell Shape Fructose 1,6-bisphosphate Metabolic Process Neutrophil Degranulation Muscle Cell Cellular Homeostasis Protein Homotetramerization Canonical Glycolysis	Glycerol-3-phosphate Metabolic Process Glycerophosphate Shuttle Glycerol Catabolic Process
Pathways		Platelet degranulation Neutrophil degranulation Glycolysis Gluconeogenesis	Synthesis of PA Triglyceride catabolism
Drugs		Zinc 1,6-Fructose Diphosphate (Linear Form) Dihydroxyacetone phosphate 1,6-DI-O-PHOSPHONO-D-MANNITOL N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Plateletcrit ( 32888494) Schizophrenia ( 25056061 29483656)	Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Depression ( 29700475) Diisocyanate-induced asthma ( 25918132) Familial squamous cell lung carcinoma ( 29924316) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Motion sickness ( 25628336) Myopia ( 27182965) Possible neuropathic pain in post total joint replacement surgery for osteoarthritis ( 28051079) Refractive error ( 32231278) Response to statin therapy ( 20339536) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Ulcerative colitis ( 25082827) Urinary albumin-to-creatinine ratio ( 31630189)
Interacting Genes		33 interacting genes: ADRB2 ALDOB ATP6V1E1 BCAT2 CACNA1A CYTH2 DYNLL1 EGFR ENO1 ENO3 ERBB2 ERBB3 ERBB4 FANCA GALNT6 GPD2 HSD17B10 HSPB2 IFNA4 LINC01554 MLH1 MYOC PCNA PIAS4 PLD2 SLC22A1 SRPK2 SUMO4 TERF1 TGM2 TRIM63 TUBB XRN1	1 interacting genes: ALDOA
Entrez ID		226	2820
HPRD ID		00070	00715
Ensembl ID		ENSG00000149925	ENSG00000115159
Uniprot IDs		P04075 V9HWN7	P43304 Q53T76
PDB IDs		1ALD 2ALD 4ALD 5KY6
Enriched GO Terms of Interacting Partners?
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