RFX6 and PATZ1

Data Source:
BioGRID (two hybrid)

		RFX6	PATZ1
Description		regulatory factor X6	POZ/BTB and AT hook containing zinc finger 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Nucleoplasm
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Ubiquitin Protein Ligase Binding Metal Ion Binding
	Biological Process	Type B Pancreatic Cell Differentiation Pancreatic A Cell Differentiation Pancreatic D Cell Differentiation Regulation Of Transcription By RNA Polymerase II Endocrine Pancreas Development Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Glucose Homeostasis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Insulin Secretion Pancreatic Epsilon Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Spermatogenesis Male Gonad Development Negative Regulation Of Endothelial Cell Migration T Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways		Regulation of gene expression in beta cells
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Chronic obstructive pulmonary disease ( 30804561) Creatine kinase levels ( 29403010) Diastolic blood pressure ( 27841878) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Height ( 31562340) Inflammatory bowel disease ( 27569725) Lung cancer ( 28604730) Neutrophil percentage of granulocytes ( 27863252) Offspring birth weight ( 31043758) Prostate cancer ( 20676098 31562322 26443449) Serum total protein level ( 29403010)	Eosinophil percentage of white cells ( 32888494) Fish- and plant-related diet ( 32066663) Height ( 31562340) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Red cell distribution width ( 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		41 interacting genes: AGXT ARNT2 CATSPER1 CCNK CSTF2 CYFIP1 DGCR6 DMRT3 DTX2 DUSP21 ESR2 FHL3 FRS3 HGS KCTD9 KIF1A LGALS4 LMO3 MEMO1 NEDD9 PATZ1 PITX1 PLEKHN1 PPP1R32 PRKAA1 PRKAA2 RFX2 RFX3 RIPK3 SNRPB SNRPC SS18L1 STK16 TEKT3 TEKT4 TENT5B TLE5 USP2 VPS37C ZMYND19 ZNF688	81 interacting genes: AKAP8L BACH1 BACH2 BOLL BPIFA1 C11orf1 C19orf54 CEP76 CLK1 CPSF7 CYSRT1 DAZAP2 DVL3 EYA2 FAM168A FAM168B GOLGA6L9 GPANK1 HNRNPF HNRNPH1 HSPB2 HSPB2-C11orf52 HYI IQUB KLF1 KLHDC7B KRT33B KRTAP12-2 KRTAP13-2 KRTAP15-1 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 LMO2 LONRF1 LURAP1L LZTS2 MDFI MITF MSX2 NFKBID NHLRC4 OIP5 PFDN5 PHF1 PPP1R16B PPP1R37 PRDM14 PRDM6 PRKAR1A PRR20A PRR20B PRR20C PRR20D PRR20E PRR22 RBM10 RBPMS RBPMS2 RFX6 RIPPLY1 RNF4 SLAIN1 SMYD1 SPAG8 TLE5 TNS2 TRAF1 TRIP6 TSC1 WWOX WWP2 ZBTB32 ZIC1 ZIM2
Entrez ID		222546	23598
HPRD ID		11490	05522
Ensembl ID		ENSG00000185002	ENSG00000100105
Uniprot IDs		Q8HWS3	A0A024R1F8 A0A024R1H7 A0A024R1M5 Q9HBE1
PDB IDs			2EPP 2EPQ 2EPR 2EPS 2YT9
Enriched GO Terms of Interacting Partners?
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