CPNE2 and NCKIPSD

Data Source:
BioGRID (two hybrid)

		CPNE2	NCKIPSD
Description		copine 2	NCK interacting protein with SH3 domain
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Extracellular Exosome	Cytosol Intermediate Filament COP9 Signalosome
	Molecular Function	Protein Binding Calcium-dependent Phospholipid Binding Metal Ion Binding	Protein Binding Cytoskeletal Protein Binding SH3 Domain Binding
	Biological Process	Cellular Response To Calcium Ion	Cytoskeleton Organization Positive Regulation Of Neuron Projection Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Pathways			Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS			Anorexia nervosa ( 31308545) Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Intelligence (MTAG) ( 29326435) Parkinson's disease ( 28892059) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		28 interacting genes: ACTB ANXA7 BCOR CDKN1A CT55 EFHC2 GBP7 IKBKG KATNBL1 LNX1 MEI4 MEOX2 MYCBP NCKIPSD PDCD6 PICK1 PPP5C RDX REL SKIL SORBS3 TCF4 TERF2IP THAP4 TRIM27 UBA3 UBE2M UBE2O	41 interacting genes: ABI2 ARHGEF7 BAIAP2 CCDC187 CPNE2 CYSLTR2 DIAPH2 DIAPH3 DLG4 DMRTB1 ENKD1 FASLG GAS7 GRB2 HSPB1 ITGB1 KHDRBS1 LGALS4 MAPK3 MED25 NCK1 NCK2 PIN1 PKP2 POLR3C PRPF31 PSMD9 PSORS1C2 RBM22 RBP7 RXFP3 SNRPC SORBS3 STAC TSEN54 VEZF1 WAS WASL YWHAG ZBTB47 ZC2HC1C
Entrez ID		221184	51517
HPRD ID		05015	09450
Ensembl ID		ENSG00000140848	ENSG00000213672
Uniprot IDs		Q96FN4	Q9NZQ3
PDB IDs			6DEC 6DED 6DEE
Enriched GO Terms of Interacting Partners?
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