RNF152 and CROCC

Data Source:
BioGRID (two hybrid)

		RNF152	CROCC
Description		ring finger protein 152	ciliary rootlet coiled-coil, rootletin
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Integral Component Of Organelle Membrane	Photoreceptor Inner Segment Centrosome Centriole Cytosol Plasma Membrane Actin Cytoskeleton Ciliary Rootlet Extracellular Exosome 9+2 Motile Cilium Subapical Part Of Cell
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Small GTPase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Actin Binding Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Kinesin Binding
	Biological Process	Apoptotic Process Positive Regulation Of Autophagy Protein Ubiquitination Cellular Response To Amino Acid Starvation Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Negative Regulation Of TORC1 Signaling	Centrosome Cycle Protein Localization Centriole-centriole Cohesion Epithelial Structure Maintenance Ciliary Basal Body Organization Protein Localization To Organelle Photoreceptor Cell Maintenance Positive Regulation Of Cilium Assembly Establishment Of Organelle Localization Positive Regulation Of Protein Localization To Cilium
Pathways		E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462 30604766) Glomerular filtration rate (creatinine) ( 28452372 26831199)	Allergic rhinitis ( 22036096) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Hematocrit ( 32888494) Lymphocyte percentage of white cells ( 32888494) Red blood cell count ( 32888494) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		10 interacting genes: CROCC EBP GJA8 KIR2DL3 RHEB RRAGA TSPAN12 UBE2E1 UBE2N UBE2W	2 interacting genes: KLC3 RNF152
Entrez ID		220441	9696
HPRD ID		11514	16758
Ensembl ID		ENSG00000176641	ENSG00000058453
Uniprot IDs		Q8N8N0	Q5TZA2
PDB IDs			6L5H 6L5J
Enriched GO Terms of Interacting Partners?
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