MTIF3 and COQ8A

Data Source:
BioGRID (two hybrid)

		MTIF3	COQ8A
Description		mitochondrial translational initiation factor 3	coenzyme Q8A
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GO Annotations	Cellular Component	Mitochondrion	Mitochondrion Integral Component Of Membrane Extrinsic Component Of Mitochondrial Inner Membrane
	Molecular Function	Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ribosome Binding Ribosomal Small Subunit Binding	Protein Kinase Activity Protein Binding ATP Binding Kinase Activity ADP Binding
	Biological Process	Ribosome Disassembly Mitochondrial Translational Initiation	Protein Phosphorylation Ubiquinone Biosynthetic Process Phosphorylation
Pathways		Mitochondrial translation initiation
Drugs			Fostamatinib
Diseases			Coenzyme Q10 deficiency Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		Adult body size ( 32376654) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 28892062 25673413 20935630) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Estimated glomerular filtration rate change in renal transplantation (recipient effect) ( 30920136) Night sleep phenotypes ( 27126917) Psychosis proneness (hypomanic personality scale and perceptual aberration scale) ( 28525603)
Interacting Genes		84 interacting genes: APOD BCL2L1 BMP10 BPIFA1 BRICD5 CABP7 CD47 CDIPT CDS2 CGRRF1 CLDND2 CLEC7A CMTM5 COL4A5 COQ8A CTXN3 CXCL9 CYBC1 CYP4F2 EPGN FBXO7 FETUB FXYD3 FXYD6-FXYD2 HSFX1 HSFX2 HTATIP2 ITGB2 JAGN1 LAPTM4B LAT LDLR LHFPL5 MAPK1 MGST3 MRFAP1 MS4A1 NAT8 NDRG4 ORMDL3 PAXIP1 PEA15 PLN PLP1 PRH1 RPRM SCD SELENOK SERP1 SERP2 SERTM1 SIAH1 SNX2 SPANXN2 STARD4 STATH STRIT1 STX3 STX6 THBD THSD7B TMED8 TMEM109 TMEM11 TMEM128 TMEM147 TMEM176A TMEM218 TMEM239 TMEM242 TMEM243 TMEM254 TMEM42 TMEM97 TRARG1 TSPAN33 TUFM UNC50 VAMP4 VEZT VKORC1L1 YIPF6 ZDHHC15 ZNF202	26 interacting genes: ABHD5 AGTRAP CCDC34 CMTM4 CMTM5 CMTM6 COQ9 DESI2 DTX2 JOSD2 MAL2 MRM1 MTIF3 ORMDL3 PBX3 RABAC1 REEP6 RPRM SH3GLB1 SMPD2 STX10 TFIP11 TMCO2 TMEM159 TMEM239 TPD52L2
Entrez ID		219402	56997
HPRD ID		17609	07375
Ensembl ID		ENSG00000122033	ENSG00000163050
Uniprot IDs		Q9H2K0	Q8NI60
PDB IDs		6NEQ 6NF8 6RW4 6RW5	4PED 5I35
Enriched GO Terms of Interacting Partners?
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