ESRRG and ARHGEF15

ESRRG

ARHGEF15

Description estrogen related receptor gamma Rho guanine nucleotide exchange factor 15
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs) ( 23648065)
  • Adverse response to drug ( 30420678)
  • Alcohol consumption ( 23743675)
  • Breast cancer ( 29059683)
  • Cardiac hypertrophy ( 21348951)
  • Cleft lip with or without cleft palate (maternal periconceptional vitamin use interaction) ( 29535761)
  • Depressive symptom (anhedonia) (ordinal trait) ( 31530331)
  • Dialysis-related mortality ( 21546767)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Energy expenditure (24h) ( 28476931)
  • General cognitive ability ( 29844566)
  • General risk tolerance (MTAG) ( 30643258)
  • Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821)
  • Hematocrit ( 32888494)
  • Hemoglobin ( 32888494)
  • Intelligence (MTAG) ( 29326435)
  • Intracranial aneurysm ( 29531279)
  • Major depressive disorder ( 23377640)
  • Mean arterial pressure (alcohol consumption interaction) ( 24376456)
  • Nicotine dependence and major depression (severity of comorbidity) ( 30287806)
  • Optic nerve measurement (cup area) ( 20395239)
  • Photic sneeze reflex ( 27182965)
  • Post bronchodilator FEV1 ( 26634245)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Refractive error ( 32231278)
  • Sleep duration ( 25469926)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Tea consumption ( 31046077)
  • Weight ( 28552196)
Interacting Genes 58 interacting genes: ADCY4 APP ARHGEF15 ATM BPHL C22orf23 CALM1 CAMK2G CCDC33 DAXX DEUP1 DUT EBP EFHC2 ESRRA ESRRB EXOSC7 FAM107A FAM9A FASTK HGS HIF1A KIFC3 LRRK2 MCC MEOX2 MFHAS1 MRM1 NCOA1 NR0B1 NR0B2 NRIP1 NUP160 PAX6 PNRC1 PNRC2 POMC PPARGC1A PPARGC1B PROX1 PSMC5 RBIS REL RINT1 SHTN1 SNIP1 SP1 SRA1 SRPK1 SUMO1P1 TLE1 TNNI1 TNNI2 TRERF1 TULP3 UBL7 VAX1 ZNF438 14 interacting genes: C11orf49 CDC42 CEP55 DNAJC5 EPHA4 ESR1 ESRRG GORASP2 LASP1 MOB4 PIN1 PRKG1 RHOA SH3RF1
Entrez ID 2104 22899
HPRD ID 04274 10535
Ensembl ID ENSG00000196482 ENSG00000198844
Uniprot IDs B7Z5E9 C0SQ93 F1D8R5 F1D8R6 P62508 A0A0S2Z547 O94989
PDB IDs 1KV6 1TFC 1VJB 2E2R 2EWP 2GP7 2GPO 2GPP 2GPU 2GPV 2P7A 2P7G 2P7Z 2ZAS 2ZBS 2ZKC 5YSO 6A6K 6I61 6I62 6I63 6I64 6I65 6I66 6I67 6K3N 6KNR
Enriched GO Terms of Interacting Partners?
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