EPHA3 and CDKN2A

EPHA3

CDKN2A

Description EPH receptor A3 cyclin dependent kinase inhibitor 2A
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Atrial fibrillation ( 30061737 29892015)
  • BMI (adjusted for smoking behaviour) ( 28443625)
  • BMI in non-smokers ( 28443625)
  • Body mass index (joint analysis main effects and smoking interaction) ( 28443625)
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Cortical surface area (MOSTest) ( 32665545)
  • Diastolic blood pressure ( 27841878)
  • Loneliness (multivariate analysis) ( 27629369)
  • Lung function (FVC) ( 26635082)
  • Orofacial clefts ( 22863734)
  • Periodontitis (Mean PAL) ( 24024966)
  • Post-bronchodilator FEV1 x air pollution (NO2) interaction in childhood asthma ( 31028280)
  • Subcortical volume (min-P) ( 32665545)
  • Subcortical volume (MOSTest) ( 32665545)
  • Systemic lupus erythematosus ( 28714469)
  • Systolic blood pressure ( 27841878)
  • Tea consumption ( 31046077)
  • Thrombosis ( 26908601)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes 29 interacting genes: ABL1 ADAM10 CDKN2A CRK CTDSP2 DUSP18 DUSP21 EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 EFNB1 EFNB2 ERBB2 FBXO7 FYN ILKAP MTMR11 PIM1 RBM18 RUFY1 RUFY2 SRC SRPK1 STAT3 STYX TP53 TPTE 168 interacting genes: - ACLY ACTB ACTG1 ACTN4 AHNAK AKT1 ALDOB ANAPC15 ANGPTL4 ANKRA2 ANKRD12 AOPEP ARFIP2 ARNT ASPRV1 AZIN1 BAAT BCL2L1 BECN1 CARF CASC3 CCDC180 CCDC183 CCND2 CCNDBP1 CCNE1 CCNG1 CD44 CDC14B CDC42 CDC45 CDC5L CDC6 CDC7 CDK4 CDK6 CDKN2AIP CDKN2B CDKN2C CENPA CRELD2 CTBP2 CTSV CYLC2 DEAF1 E2F1 E4F1 EEF2 EFHC2 EGR1 EPHA2 EPHA3 EXOC2 FGFR4 FN1 FRAT2 FZR1 GALNT12 GAPDH GGA1 GGA3 GLIS1 GLIS2 GMNN GSPT1 H2BU1 HGF HIF1A HLA-DOB HNRNPA2B1 HNRNPC HNRNPU HRAS HSP90AA1 HSP90AB1 HSPA4 HSPA8 HUWE1 ISOC2 KAT5 LATS2 MAF1 MAP2K1 MAP2K5 MAP3K5 MAPK10 MAPK14 MAPK3 MAPK8 MCM10 MCM2 MCM5 MCM6 MDM2 MDM4 MMRN1 MTR MYC MYL12A NAT2 NCL NMI NOP53 NPM1 NSD3 ORC4 PCNA PDCD6 PDGFRA PEX19 PPP1R9B PRKCA PSMC3 PTP4A3 RAF1 RASA1 RASSF1 RBM26 RIN2 RPL11 RPS7 RUVBL2 SEC61B SERTAD1 SFRP4 SIVA1 SIX2 SLC4A1 SMARCA4 SNRPA SNRPB SOX3 SOX4 STK11 TBRG1 TDRD7 TEAD2 TERT TFDP1 TGFB1 TMEFF1 TMOD1 TP53 TP63 TPI1 TRIM28 TRIP12 TSC1 TUBA1A TUBA1C TUBB TUBB4B UBE2A UBE4B UBL7 USP26 VAMP1 VHL WRN YY1 ZFP91 ZGRF1 ZNF227 ZNF410 ZNF420 ZNF687 ZUP1
Entrez ID 2042 1029
HPRD ID 01555 02542
Ensembl ID ENSG00000044524 ENSG00000147889
Uniprot IDs A0A140VJJ0 C9JXA2 P29320 Q6P4R6 K7PML8 P42771 Q8N726
PDB IDs 2GSF 2QO2 2QO7 2QO9 2QOB 2QOC 2QOD 2QOF 2QOI 2QOK 2QOL 2QON 2QOO 2QOQ 3DZQ 3FXX 3FY2 4G2F 4GK2 4GK3 4GK4 4L0P 4P4C 4P5Q 4P5Z 4TWN 4TWO 6IN0 1A5E 1BI7 1DC2 2A5E
Enriched GO Terms of Interacting Partners?
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