ENO2 and NDUFS7

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ENO2	NDUFS7
Description		enolase 2	NADH:ubiquinone oxidoreductase core subunit S7
Image
GO Annotations	Cellular Component	Phosphopyruvate Hydratase Complex Photoreceptor Inner Segment Extracellular Space Cytosol Plasma Membrane Membrane Perikaryon Extracellular Exosome	Mitochondrial Respiratory Chain Complex I Mitochondrial Matrix
	Molecular Function	Magnesium Ion Binding Phosphopyruvate Hydratase Activity Protein Binding	NADH Dehydrogenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor Metal Ion Binding Quinone Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Gluconeogenesis Glycolytic Process Regulation Of Vacuole Fusion, Non-autophagic Canonical Glycolysis	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Electron Transport Coupled Proton Transport Mitochondrial Respiratory Chain Complex I Assembly
Pathways		Glycolysis Gluconeogenesis	Respiratory electron transport Complex I biogenesis
Drugs		2-Phosphoglycolic Acid	NADH
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS
Interacting Genes		25 interacting genes: A2M ACD AKT1 ANXA11 BMERB1 C6orf47 ENSA EXOC5 HABP4 HK1 HSF1 IL17B MAP4 MTNR1A NAT9 NDUFS7 POT1 SIGIRR SNUPN ST3GAL2 SUMO4 TERF1 TINF2 TUBA4A UBE2C	3 interacting genes: ARRB2 ENO2 MT-ND1
Entrez ID		2026	374291
HPRD ID		00573	03491
Ensembl ID		ENSG00000111674	ENSG00000115286
Uniprot IDs		P09104 Q6FHV6	O75251 Q6ZS38 Q7LD69
PDB IDs		1TE6 2AKM 2AKZ 3UCC 3UCD 3UJE 3UJF 3UJR 3UJS 4ZA0 4ZCW 5EU9 5IDZ 5TD9 5TIJ	5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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