SPATA24 and CTNNBIP1

Data Source:
BioGRID (two hybrid)

		SPATA24	CTNNBIP1
Description		spermatogenesis associated 24	catenin beta interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol Beta-catenin Destruction Complex
	Molecular Function	DNA Binding Protein Binding	Protein Binding Beta-catenin Binding Armadillo Repeat Domain Binding
	Biological Process	Multicellular Organism Development Spermatogenesis Cell Differentiation	Branching Involved In Ureteric Bud Morphogenesis Regulation Of Vascular Permeability Involved In Acute Inflammatory Response Anterior/posterior Pattern Specification Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Protein Binding Negative Regulation Of DNA Binding Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Monocyte Differentiation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Mesenchymal Cell Proliferation
Pathways			Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS		Body mass index ( 26426971) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Malaria ( 31844061)	Platelet distribution width ( 32888494) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		24 interacting genes: CALCOCO2 CAMK2D CEP72 CTNNBIP1 CYSRT1 EFEMP2 EHD2 FLOT2 KDM1A KRT31 KRT40 KRTAP10-1 KRTAP10-7 KRTAP10-8 KRTAP4-2 LZTS2 MDFI MID2 NBPF19 NOTCH2NLA OIP5 PLEKHF2 PTAFR SUV39H1	19 interacting genes: BEND5 CTNNA2 CTNNB1 EMD GINS4 INCA1 JUP KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP5-9 MSS51 NBPF19 NOTCH2NLA P4HA3 REL SPATA24 TCF7L2 USHBP1
Entrez ID		202051	56998
HPRD ID		19510	09677
Ensembl ID		ENSG00000170469	ENSG00000178585
Uniprot IDs		Q86W54	A0A024R4D7 Q9NSA3
PDB IDs			1LUJ 1M1E 1T08
Enriched GO Terms of Interacting Partners?
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