ZSCAN4 and LAMTOR3

Data Source:
BioGRID (two hybrid)

		ZSCAN4	LAMTOR3
Description		zinc finger and SCAN domain containing 4	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus	Lysosomal Membrane Plasma Membrane Focal Adhesion Endosome Membrane Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane Ragulator Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Kinase Activator Activity Molecular Adaptor Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Mitotic Recombination	MAPK Cascade Activation Of MAPKK Activity Cell Cycle Arrest Regulation Of Macroautophagy Positive Regulation Of TOR Signaling Cellular Protein Localization Neutrophil Degranulation Cellular Response To Amino Acid Stimulus Protein Localization To Cell Junction
Pathways			Macroautophagy MTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes MAP2K and MAPK activation Neutrophil degranulation Regulation of PTEN gene transcription Amino acids regulate mTORC1
Drugs
Diseases
GWAS			Mean reticulocyte volume ( 32888494)
Interacting Genes		13 interacting genes: CIB3 CTBP2 EXOC8 FAM110A HAT1 HCK KAT5 LAMTOR3 PARD6B SMAD1 SMAD9 TBC1D22B TRAF3	20 interacting genes: ADAMTS10 APOL6 BHMT CEBPZ CPNE6 IBTK LAMTOR2 MAP2K1 MAP2K2 MAPK1 MAPK3 MBD2 NIF3L1 PDE4DIP QARS1 SUFU TFE3 TGM7 UBR1 ZSCAN4
Entrez ID		201516	8649
HPRD ID		15899	04485
Ensembl ID		ENSG00000180532	ENSG00000109270
Uniprot IDs		Q8NAM6	Q9UHA4
PDB IDs			1SKO 2ZL1 3CPT 5X6U 5X6V 5Y39 5Y3A 6B9X 6EHP 6EHR 6NZD 6U62 6ULG 6WJ2 6WJ3
Enriched GO Terms of Interacting Partners?
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