KCTD6 and TBC1D2

Data Source:
BioGRID (two hybrid)

		KCTD6	TBC1D2
Description		potassium channel tetramerization domain containing 6	TBC1 domain family member 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol M Band	Nucleoplasm Cytosol Plasma Membrane Cell Junction Cytoplasmic Vesicle
	Molecular Function	Protein Binding Ankyrin Binding Identical Protein Binding Cullin Family Protein Binding	GTPase Activator Activity Protein Binding Cadherin Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Growth Post-translational Protein Modification Negative Regulation Of Smoothened Signaling Pathway Protein Homooligomerization	Intracellular Protein Transport Positive Regulation Of GTPase Activity Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		RUNX1 regulates estrogen receptor mediated transcription Neddylation Estrogen-dependent gene expression Antigen processing: Ubiquitination & Proteasome degradation	TBC/RABGAPs
Drugs
Diseases
GWAS		Hepcidin/transferrin saturation ratio ( 27846281) Refractive error ( 32231278) Systemic lupus erythematosus ( 28714469) vWF levels ( 30586737)	Metabolite levels ( 23823483) Post-traumatic stress disorder ( 26114229) Rate of ventricular enlargement ( 31711042) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		28 interacting genes: ACTN1 ACTN3 ANK1 BAG4 C8orf33 CDC23 CTNND1 CUL3 EHHADH ERBB2 FAM124B GOLGA8EP GOLGA8F GRB7 GSDMD LNX1 MOS NTAQ1 PICK1 PPIG PRPF31 PSMA1 REL SDCBP TBC1D2 TCEANC TEPSIN ZCCHC10	9 interacting genes: AURKA BUB1 CCND1 DCC GABARAPL1 KCTD6 MAP1LC3A MLH3 PDGFRL
Entrez ID		200845	55357
HPRD ID		13769	11624
Ensembl ID		ENSG00000168301	ENSG00000095383
Uniprot IDs		Q8NC69	A0A024R166 Q9BYX2
PDB IDs			2DHK
Enriched GO Terms of Interacting Partners?
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