ELF3 and MED23

Data Source:
HPRD (in vitro)

		ELF3	MED23
Description		E74 like ETS transcription factor 3	mediator complex subunit 23
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Golgi Apparatus Cytosol	Nucleoplasm Transcription Regulator Complex Mediator Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	Blastocyst Development Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Inflammatory Response Cell Differentiation Extracellular Matrix Organization Epithelial Cell Differentiation Positive Regulation Of Notch Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Mammary Gland Involution	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated
Pathways		Pre-NOTCH Transcription and Translation	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS			L-arginine levels ( 25245031) Type 2 diabetes ( 30054458)
Interacting Genes		15 interacting genes: AR CREBBP EGFR EP300 EPS15 JUN MED23 MYC NFKB1 PAK1 SOX9 TAF9 TBP XRCC5 XRCC6	15 interacting genes: CEBPB CTDP1 ELF3 ESR1 ESR2 ETS1 FOXJ3 MED13 MED9 NCOA6 PUM2 RELA SREBF1 VDR WDTC1
Entrez ID		1999	9439
HPRD ID		03722	05436
Ensembl ID		ENSG00000163435	ENSG00000112282
Uniprot IDs		A0A024R974 P78545	Q05DL5 Q9ULK4
PDB IDs		2E8P	6H02
Enriched GO Terms of Interacting Partners?
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