ELF1 and NFYA

Data Source:
BioGRID (pull down)

		ELF1	NFYA
Description		E74 like ETS transcription factor 1	nuclear transcription factor Y subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Chromatin Nucleus Nucleoplasm CCAAT-binding Factor Complex Protein-DNA Complex RNA Polymerase II Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Regulation Of Cytokine-mediated Signaling Pathway Regulation Of Transcription By RNA Polymerase II Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of B Cell Receptor Signaling Pathway	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Rhythmic Process
Pathways		RUNX1 regulates transcription of genes involved in BCR signaling RUNX1 regulates transcription of genes involved in interleukin signaling	PPARA activates gene expression Activation of gene expression by SREBF (SREBP) Activation of gene expression by SREBF (SREBP) ATF4 activates genes in response to endoplasmic reticulum stress ATF6 (ATF6-alpha) activates chaperone genes ATF6 (ATF6-alpha) activates chaperone genes FOXO-mediated transcription of cell death genes
Drugs
Diseases
GWAS		Cervical cancer ( 28806749) Crohn's disease ( 23266558) Eosinophil percentage of white cells ( 32888494) Height ( 31562340) Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494 27863252) Platelet count ( 32888494) Plateletcrit ( 32888494) Systemic lupus erythematosus ( 27399966 23273568 21044949) Total cholesterol levels ( 30275531)	Mean spheric corpuscular volume ( 32888494) White blood cell count ( 27863252)
Interacting Genes		10 interacting genes: HMGA1 HOXC13 NFKB1 NFYA NFYB NFYC RB1 REL RUNX1 SP1	48 interacting genes: APP APPBP2 ATF6 ATF6B ATXN1 BANP BRCA1 CCNA2 CDC25A CDK2 CDKN1A CEBPA CSNK2A1 DVL3 E2F6 ELF1 GTF2A1 HMGA1 JUN KPNB1 LUC7L2 NFYB NFYC NR5A1 PAPOLG POGZ POU2F1 POU3F2 PWP1 QRICH1 SP1 SPI1 SREBF2 SRF SRSF1 TAF11 TAF12 TAF6 TCAF1 TP53 UBL5 USF1 USF2 VEZF1 ZC3H10 ZHX1 ZHX2 ZHX3
Entrez ID		1997	4800
HPRD ID		01808	01793
Ensembl ID		ENSG00000120690	ENSG00000001167
Uniprot IDs		A0A024RDU6 P32519 Q6MZZ4	A0A024RD22 P23511
PDB IDs			4AWL 6QMP 6QMQ 6QMS
Enriched GO Terms of Interacting Partners?
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