EIF5A and GSC2

Data Source:
BioGRID (two hybrid)

		EIF5A	GSC2
Description		eukaryotic translation initiation factor 5A	goosecoid homeobox 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Annulate Lamellae Nuclear Pore Cytoplasm Endoplasmic Reticulum Membrane Cytosol Membrane	Chromatin Nucleus
	Molecular Function	RNA Binding Translation Elongation Factor Activity Protein Binding U6 SnRNA Binding Ribosome Binding Protein N-terminus Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	MRNA Export From Nucleus Translational Elongation Protein Export From Nucleus Nucleocytoplasmic Transport Apoptotic Process Positive Regulation Of Cell Population Proliferation Positive Regulation Of Translational Elongation Positive Regulation Of Translational Termination	Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis
Pathways		Hypusine synthesis from eIF5A-lysine
Drugs
Diseases
GWAS		Venous thromboembolism ( 31420334)	Metabolite levels ( 22916037)
Interacting Genes		17 interacting genes: CRX DHPS DOHH GSC2 LBX1 MEI4 MEOX2 PICK1 REL RPL5 SDCBP STUB1 SUMO2 TGM2 XPO1 XPO4 XRN2	60 interacting genes: ALPP ANXA5 ASPH BEST3 BNIP2 C19orf47 C1D CALM1 CALM2 CALM3 CALR CDKN2D CIAO2A COL8A1 CRCP CSNK2A1 DYRK1B EGLN3 EIF5A ETFDH FAM221B FKBP6 GALNT11 GCM2 GTF2H5 GTSF1L GUCA1A GUCY1A2 HMBOX1 ISX KDM6A KLHL38 KRT34 KRTAP5-9 LCE3E LTO1 MAD2L2 MAPK9 MARF1 MID2 MORF4L1 MRPL53 MRPS23 NME7 PACSIN2 PDE4C PRKAB2 PTER RNF4 SCAF1 SDCBP TIPIN TNPO2 TSR2 UBE2R2 VCX2 XRCC4 YPEL5 ZNF444 ZNF587
Entrez ID		1984	2928
HPRD ID		02555	03506
Ensembl ID		ENSG00000132507	ENSG00000063515
Uniprot IDs		P63241	O15499
PDB IDs		1FH4 3CPF 5DLQ
Enriched GO Terms of Interacting Partners?
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