LDHD and CSRP3

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		LDHD	CSRP3
Description		lactate dehydrogenase D	cysteine and glycine rich protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane	Nucleus Cytoplasm Cytoskeleton Z Disc
	Molecular Function	D-lactate Dehydrogenase (cytochrome) Activity Protein Binding D-lactate Dehydrogenase Activity Flavin Adenine Dinucleotide Binding FAD Binding	Actin Binding Protein Binding Structural Constituent Of Muscle Telethonin Binding Identical Protein Binding Actinin Binding Metal Ion Binding
	Biological Process	Lactate Catabolic Process	Regulation Of The Force Of Heart Contraction Cardiac Muscle Hypertrophy Cellular Calcium Ion Homeostasis Inflammatory Response Skeletal Muscle Tissue Development Insulin Receptor Signaling Pathway Actin Cytoskeleton Organization T-tubule Organization Protein Localization To Organelle Detection Of Muscle Stretch Glucose Homeostasis Sarcomere Organization Positive Regulation Of Transcription By RNA Polymerase II Cardiac Muscle Tissue Development Cardiac Myofibril Assembly Cardiac Muscle Contraction Muscle Tissue Development Protein Kinase C Signaling Regulation Of Protein Localization To Plasma Membrane
Pathways		Mitochondrial protein import Mitochondrial protein import
Drugs
Diseases			Hypertrophic cardiomyopathy (HCM)
GWAS		Crohn's disease (time to surgery) ( 23665963) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Pancreatic cancer ( 25086665) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Mosquito bite size ( 28199695) Red blood cell count ( 32888494 27863252)
Interacting Genes		1 interacting genes: CSRP3	11 interacting genes: ACTN1 FHL1 HDAC4 LDHD LIMS1 MYF6 MYOD1 MYOG NHLH1 RIN3 SPTB
Entrez ID		197257	8048
HPRD ID		06318	07525
Ensembl ID		ENSG00000166816	ENSG00000129170
Uniprot IDs		Q86WU2	A2TDB8 P50461
PDB IDs			2O10 2O13
Enriched GO Terms of Interacting Partners?
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