EFNB3 and AATF

Data Source:
BioGRID (two hybrid)

		EFNB3	AATF
Description		ephrin B3	apoptosis antagonizing transcription factor
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse Integral Component Of Presynaptic Membrane Integral Component Of Postsynaptic Density Membrane	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Cytoplasm Golgi Apparatus
	Molecular Function	Virus Receptor Activity Transmembrane-ephrin Receptor Activity Protein Binding Ephrin Receptor Binding	RNA Binding Protein Binding Protein Kinase Binding Leucine Zipper Domain Binding Tau Protein Binding
	Biological Process	Cell-cell Signaling Nervous System Development Axon Guidance Adult Walking Behavior Axon Choice Point Recognition T Cell Costimulation Viral Entry Into Host Cell Ephrin Receptor Signaling Pathway Negative Regulation Of Axonogenesis Trans-synaptic Signaling By Trans-synaptic Complex, Modulating Synaptic Transmission	Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Cell Adhesion Regulation Of Mitotic Cell Cycle Negative Regulation Of Superoxide Anion Generation Embryonic Cleavage Ribosome Biogenesis Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Apoptotic Signaling Pathway
Pathways		EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells	NRAGE signals death through JNK
Drugs
Diseases
GWAS		Alcohol consumption ( 31358974)	Body mass index ( 26426971) Erectile dysfunction ( 30583798) Obesity-related traits ( 23251661) Thyroid volume in Hashimotoâ€™s thyroiditis ( 32019955)
Interacting Genes		8 interacting genes: AATF ELOC EPHA4 EPHB3 P2RX7 RELN RHBDL2 YWHAZ	28 interacting genes: ATM ATR AURKA CHEK1 CHEK2 CPD DAPK3 DAZAP2 EFNB3 FBXO7 HIPK2 LDOC1 LZTR1 MAPT MPHOSPH6 NEDD4L NGDN PALS2 PAWR PCBD2 POLR2J RB1 RELA SMAD3 SP1 SS18L1 TSG101 ZNF468
Entrez ID		1949	26574
HPRD ID		03804	12236
Ensembl ID		ENSG00000108947	ENSG00000275700
Uniprot IDs		Q15768	Q9NY61
PDB IDs		4BKF	5W6A
Enriched GO Terms of Interacting Partners?
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