EFNB2 and GRIP1

Data Source:
HPRD (in vitro)

		EFNB2	GRIP1
Description		ephrin B2	glutamate receptor interacting protein 1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Adherens Junction Focal Adhesion Glutamatergic Synapse Integral Component Of Presynaptic Membrane	Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Postsynaptic Density Dendrite Cytoplasmic Vesicle Neuron Projection Perikaryon Membrane Raft Postsynaptic Membrane Glutamatergic Synapse
	Molecular Function	Virus Receptor Activity Protein Binding Ephrin Receptor Binding	Protein Binding Beta-catenin Binding Protein C-terminus Binding Signaling Receptor Complex Adaptor Activity Glucocorticoid Receptor Binding
	Biological Process	Cell Migration Involved In Sprouting Angiogenesis Cell Adhesion Cell-cell Signaling Axon Guidance Positive Regulation Of Cell Population Proliferation Anatomical Structure Morphogenesis Negative Regulation Of Neuron Projection Development Viral Entry Into Host Cell Ephrin Receptor Signaling Pathway Blood Vessel Morphogenesis Regulation Of Chemotaxis Presynapse Assembly Positive Regulation Of Neuron Death Positive Regulation Of Cardiac Muscle Cell Differentiation	Dendrite Development Intracellular Signal Transduction Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Positive Regulation Of Neuron Projection Arborization
Pathways		EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells	Trafficking of GluR2-containing AMPA receptors
Drugs
Diseases
GWAS		Left superior temporal gyrus thickness (schizophrenia interaction) ( 26249676) Metabolite levels ( 23823483) Pediatric autoimmune diseases ( 26301688) Subcutaneous adipose tissue ( 26480920)	Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		23 interacting genes: ANKRD46 DLG4 EPHA3 EPHA4 EPHB1 EPHB2 EPHB4 EPHB6 GRIP1 GRM1 GRM5 HOMER1 NCK2 PDZRN3 PECAM1 PICK1 PSEN1 PTPN13 RELN RGS3 RHBDL2 SDCBP SRC	42 interacting genes: AGAP2 AR CARM1 CSPG4 DEPDC1B DZIP3 EEPD1 EFNA5 EFNB1 EFNB2 EP300 ESR1 FGF12 FLII GPR37 GRIA1 GRIA3 GRIA4 GRIK1 GRIK2 GRIPAP1 GRM2 GRM3 GRM7 H3C1 HUS1 IRF3 MFAP3 NCOA6 NEK6 NR3C1 NUMBL PICK1 PPARG PRKD2 PRMT1 RXRA THRA UBE2I VDR WDR6 XDH
Entrez ID		1948	23426
HPRD ID		02754	19086
Ensembl ID		ENSG00000125266	ENSG00000155974
Uniprot IDs		P52799	Q9Y3R0
PDB IDs		2HLE 2I85 2VSK 2VSM 2WO2 3GXU 4UF7 6P7Y 6PDL	2JIL
Enriched GO Terms of Interacting Partners?
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