EFNA3 and CD48

Data Source:
BioGRID (affinity chromatography technology)

		EFNA3	CD48
Description		ephrin A3	CD48 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Anchored Component Of Membrane Intrinsic Component Of Plasma Membrane	Plasma Membrane Membrane Anchored Component Of Membrane Intrinsic Component Of Plasma Membrane Membrane Raft Extracellular Exosome
	Molecular Function	Transmembrane-ephrin Receptor Activity Protein Binding Ephrin Receptor Binding	Antigen Binding Protein Binding Signaling Receptor Activity
	Biological Process	Cell-cell Signaling Axon Guidance Negative Regulation Of Angiogenesis Regulation Of Neuron Differentiation Ephrin Receptor Signaling Pathway Positive Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process	Regulation Of Adaptive Immune Response Defense Response Leukocyte Migration
Pathways		EPH-Ephrin signaling EPH-Ephrin signaling EPHA-mediated growth cone collapse EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells EPH-ephrin mediated repulsion of cells	Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cataracts (operation) ( 31816047) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Optic disc size ( 31809533) Prostate cancer ( 23535732) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urinary albumin excretion ( 30220432)	Blood protein levels ( 30072576 29875488) Inflammatory bowel disease ( 23128233) Itch intensity from mosquito bite ( 28199695) Multiple sclerosis ( 31604244) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		11 interacting genes: EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 KRTAP1-1 KRTAP10-3 LCE2C MEOX2 NOTCH2NLA PRSS23	10 interacting genes: BRIX1 CD2 CD244 CD247 EEF1D FYN GNAI3 IL18R1 IL18RAP LCK
Entrez ID		1944	962
HPRD ID		03225	00177
Ensembl ID		ENSG00000143590	ENSG00000117091
Uniprot IDs		P52797	A0A087X1S7 P09326
PDB IDs			2EDO
Enriched GO Terms of Interacting Partners?
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