SCAMP5 and GDNF

Data Source:
BioGRID (two hybrid)

		SCAMP5	GDNF
Description		secretory carrier membrane protein 5	glial cell derived neurotrophic factor
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Plasma Membrane Integral Component Of Membrane Synaptic Vesicle Membrane Trans-Golgi Network Membrane Recycling Endosome Membrane	Extracellular Region Extracellular Space Golgi Apparatus
	Molecular Function	Protein Binding Protein-containing Complex Binding	Signaling Receptor Binding Protein Binding Growth Factor Activity Glial Cell-derived Neurotrophic Factor Receptor Binding Receptor Tyrosine Kinase Binding Protein Homodimerization Activity Chemoattractant Activity Involved In Axon Guidance
	Biological Process	Positive Regulation Of Cytokine Production Exocytosis Protein Transport Response To Endoplasmic Reticulum Stress Negative Regulation Of Endocytosis Positive Regulation Of Calcium Ion-dependent Exocytosis	MAPK Cascade Metanephros Development Branching Involved In Ureteric Bud Morphogenesis Neural Crest Cell Migration Organ Induction Postsynaptic Membrane Organization Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Signal Transduction Nervous System Development Axon Guidance Peripheral Nervous System Development Positive Regulation Of Cell Population Proliferation Adult Locomotory Behavior Regulation Of Gene Expression Dorsal Spinal Cord Development Postganglionic Parasympathetic Fiber Development Peristalsis Neuron Projection Development Positive Regulation Of Monooxygenase Activity Positive Regulation Of Dopamine Secretion Negative Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II MRNA Stabilization Enteric Nervous System Development Sympathetic Nervous System Development Embryonic Organ Development Regulation Of Dopamine Uptake Involved In Synaptic Transmission Ureteric Bud Formation Regulation Of Morphogenesis Of A Branching Structure Chemoattraction Of Axon Commissural Neuron Axon Guidance Positive Regulation Of Ureteric Bud Formation Positive Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Regulation Of Stem Cell Differentiation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Semaphorin-plexin Signaling Pathway
Pathways			NCAM1 interactions RAF/MAP kinase cascade RET signaling
Drugs			Chondroitin sulfate
Diseases			Hirschsprung disease (HD) Congenital central hypoventilation syndrome (CCHS)
GWAS		Blood trace element (Zn levels) ( 23720494) Caffeine consumption ( 21490707) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) LDL cholesterol ( 30275531) Mean corpuscular volume ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Systemic lupus erythematosus ( 26502338) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Asthma ( 29273806) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Major depressive disorder ( 20125088)
Interacting Genes		23 interacting genes: AQP6 ARFIP2 CERS4 CREB3 DNAJC5 FATE1 GDNF HSD17B13 MUC1 PAXIP1 PIGP PITPNC1 PLAU SGPL1 SH3GL1 SHISAL1 SLC10A6 SLC9A7 TIMMDC1 TLCD4 TMEM14B TMX2 TTPA	8 interacting genes: AGTRAP GFRA1 GFRA2 MUC1 NCAM1 RET SCAMP5 SYP
Entrez ID		192683	2668
HPRD ID		18020	02906
Ensembl ID		ENSG00000198794	ENSG00000168621
Uniprot IDs		A0A0A8K8F5 Q8TAC9	A0A0S2Z3T2 A0A0S2Z3V2 P39905
PDB IDs			2V5E 3FUB 4UX8 6Q2N
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?