ECT2 and MT-CO2

Data Source:
BioGRID (two hybrid)

		ECT2	MT-CO2
Description		epithelial cell transforming 2	cytochrome c oxidase subunit II
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cell-cell Junction Bicellular Tight Junction Cell Cortex Nuclear Body Midbody Cleavage Furrow Mitotic Spindle Centralspindlin Complex	Mitochondrion Mitochondrial Inner Membrane Membrane Integral Component Of Membrane Respiratory Chain Complex IV
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding Small GTPase Binding Protein Homodimerization Activity	Cytochrome-c Oxidase Activity Copper Ion Binding Protein Binding
	Biological Process	Mitotic Cytokinesis Cell Morphogenesis G Protein-coupled Receptor Signaling Pathway Nervous System Development Protein Transport Cell Differentiation Activation Of Protein Kinase Activity Positive Regulation Of Cytokinesis Intracellular Signal Transduction Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of GTPase Activity Positive Regulation Of Neuron Differentiation Regulation Of Protein Kinase Activity Regulation Of Small GTPase Mediated Signal Transduction Protein Homooligomerization Regulation Of Attachment Of Spindle Microtubules To Kinetochore Cellular Response To Hydrogen Peroxide Bicellular Tight Junction Assembly Cellular Response To Calcium Ion Cellular Response To Ionizing Radiation Activation Of GTPase Activity Regulation Of Cytokinesis, Actomyosin Contractile Ring Assembly	Mitochondrial Electron Transport, Cytochrome C To Oxygen Lactation Response To Cold Positive Regulation Of Hydrogen Peroxide Biosynthetic Process Positive Regulation Of Necrotic Cell Death ATP Synthesis Coupled Electron Transport Proton Transmembrane Transport Positive Regulation Of ATP Biosynthetic Process
Pathways		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events	TP53 Regulates Metabolic Genes Respiratory electron transport
Drugs			Cholic Acid N-Formylmethionine Talmapimod
Diseases
GWAS		Obesity-related traits ( 23251661) Red cell distribution width ( 32888494)
Interacting Genes		38 interacting genes: ABR C2orf42 CCDC91 CD19 CDK1 CHST10 CSTB EIF4A2 EIF5B ELOC ERAL1 F2RL2 FANCM GGN ILVBL KLHL20 LAMTOR5 MBD1 MT-CO2 MT2A NOMO1 NPC2 OOSP2 OTUB1 PARD6A PCOLCE PLK1 POMP PSMA6 RACGAP1 RHOG RPS20 SNRNP200 SPATA22 SRPK2 THAP11 UBB VDAC2	9 interacting genes: CCNG1 ECT2 EGFR HSPB2 LIG4 PSMA1 RAD21 RIDA YWHAE
Entrez ID		1894	4513
HPRD ID		11860	02470
Ensembl ID		ENSG00000114346	ENSG00000198712
Uniprot IDs		Q9H8V3	A0A1X7RBF7 P00403 U5Z487
PDB IDs		3L46 4N40 6L30	3VRJ 5Z62
Enriched GO Terms of Interacting Partners?
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