DPH2 and MISP

		DPH2	MISP
Description		diphthamide biosynthesis 2	mitotic spindle positioning
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Actin Filament Plasma Membrane Focal Adhesion Cortical Actin Cytoskeleton Spindle Pole Centrosome Intracellular Membrane-bounded Organelle Mitotic Spindle Astral Microtubule End
	Molecular Function	Protein Binding 2-(3-amino-3-carboxypropyl)histidine Synthase Activity	Protein Binding Actin Filament Binding
	Biological Process	Peptidyl-diphthamide Biosynthetic Process From Peptidyl-histidine	Establishment Of Mitotic Spindle Orientation Cell Migration Cell Division Organelle Localization Establishment Of Centrosome Localization Mitotic Spindle Assembly Regulation Of Protein Localization To Cell Cortex
Pathways		Synthesis of diphthamide-EEF2
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		7 interacting genes: CRYGA FARS2 IL17A MAGOH MISP NEK6 TNK2	49 interacting genes: BHLHB9 BLZF1 C19orf54 CCDC33 CDPF1 CEP76 CRBN DPH2 DPPA4 EFHC2 ENKD1 EZR FHL2 FHL5 GOLGA2 HNRNPK HSF2BP HSPB2 HSPB2-C11orf52 HSPB8 IKZF3 IRAK1BP1 KRTAP12-3 LMO1 LMO2 MAP1LC3C MORN3 MORN5 OIP5 PAX6 PFDN5 PIH1D1 PIH1D2 PNMA2 PPP1R16B PRR5L RIBC1 RINT1 RUSC1 SNW1 SOCS7 SPATC1L SPATS1 TERF1 TRAF2 TRIB3 TRIP6 VBP1 ZNF620
Entrez ID		1802	126353
HPRD ID		16023	12695
Ensembl ID		ENSG00000132768	ENSG00000099812
Uniprot IDs		B3KRB8 Q9BQC3	Q8IVT2
PDB IDs
Enriched GO Terms of Interacting Partners?
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