DXO and FLOT2

Data Source:
HPRD (two hybrid)

		DXO	FLOT2
Description		decapping exoribonuclease	flotillin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Plasma Membrane	Uropod Endosome Plasma Membrane Caveola Adherens Junction Focal Adhesion Membrane Basolateral Plasma Membrane Apical Plasma Membrane Flotillin Complex Lamellipodium Endocytic Vesicle Cortical Actin Cytoskeleton Cytoplasmic Vesicle Vesicle Intracellular Membrane-bounded Organelle Cell-cell Contact Zone Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Nucleotide Binding Magnesium Ion Binding MRNA Binding 5'-3' Exonuclease Activity RNA Pyrophosphohydrolase Activity RNA NAD-cap (NAD-forming) Hydrolase Activity	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Destabilization Nuclear MRNA Surveillance Nucleic Acid Phosphodiester Bond Hydrolysis NAD-cap Decapping	Membrane Raft Assembly Cell Adhesion Epidermis Development Negative Regulation Of Gene Expression Regulation Of Heterotypic Cell-cell Adhesion Regulation Of Toll-like Receptor 3 Signaling Pathway Protein Localization To Plasma Membrane Raft Regulation Of Myoblast Differentiation Protein Stabilization Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Localization To Plasma Membrane Negative Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of Establishment Of T Cell Polarity
Pathways			RIPK1-mediated regulated necrosis Regulation of necroptotic cell death Synaptic adhesion-like molecules
Drugs
Diseases
GWAS		Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Disease progression in age-related macular degeneration ( 29346644) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)	Mean corpuscular hemoglobin ( 29403010) Red blood cell count ( 27863252)
Interacting Genes		8 interacting genes: EXOSC10 EXOSC4 EXOSC7 FLOT2 PRMT6 UPF1 XRN1 XRN2	11 interacting genes: APP CAV1 CAV2 DXO FLOT1 FYN HGS MAGEB4 NMNAT1 SPATA24 UBC
Entrez ID		1797	2319
HPRD ID		16186	00580
Ensembl ID		ENSG00000204348	ENSG00000132589
Uniprot IDs		A0A024RCW8 O77932	A0A024QZ62 J3QLD9 Q14254 Q6FG43 Q9BTI6
PDB IDs
Enriched GO Terms of Interacting Partners?
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