FAM9A and KMT5A

Data Source:
BioGRID (two hybrid)

		FAM9A	KMT5A
Description		family with sequence similarity 9 member A	lysine methyltransferase 5A
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Nucleolus	Nucleoplasm Chromosome Cytosol
	Molecular Function	Protein Binding	P53 Binding Transcription Corepressor Activity Protein Binding Lysine N-methyltransferase Activity Protein-lysine N-methyltransferase Activity Histone-lysine N-methyltransferase Activity Histone Methyltransferase Activity (H4-K20 Specific)
	Biological Process	Spermatid Development Meiotic Cell Cycle	Negative Regulation Of Transcription By RNA Polymerase II Cell Cycle Peptidyl-lysine Monomethylation Histone H4-K20 Methylation Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Transcription, DNA-templated Cell Division Regulation Of Signal Transduction By P53 Class Mediator
Pathways			Condensation of Prophase Chromosomes PKMTs methylate histone lysines Regulation of TP53 Activity through Methylation
Drugs
Diseases
GWAS		Age at voice drop ( 27182965) Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Hematocrit ( 29403010) Hemoglobin ( 29403010) Male-pattern baldness ( 27182965)	Autism spectrum disorder or schizophrenia ( 28540026) High density lipoprotein cholesterol levels ( 29403010)
Interacting Genes		39 interacting genes: ARPC3 CTNNA3 ESRRA ESRRG FAM9B H2BC15 HOMER1 INTS12 KDM1A KMT5A LCE1E MCRS1 MLLT3 NAB2 NXF1 PHC1 PICK1 PRMT1 PRR20A PRR20B PRR20C PRR20D PRR20E RNF151 RNF4 RUNX1T1 SDCBP STAC3 THAP1 TRAF2 TRAF5 TRIM41 TRIM54 TXLNA VCX ZBTB6 ZDHHC17 ZFP91 ZNF775	11 interacting genes: BTRC DTL E2F2 FAM9A H4-16 PCNA TCF7L2 TP53 TWIST1 UBE2I USP17L2
Entrez ID		171482	387893
HPRD ID		06506	06254
Ensembl ID		ENSG00000183304	ENSG00000183955
Uniprot IDs		Q8IZU1	E3VVS3 Q9NQR1
PDB IDs			1ZKK 2BQZ 3F9W 3F9X 3F9Y 3F9Z 4IJ8 5HQ2 5T5G 5TEG 5TH7 5V2N 5W1Y 6BOZ
Enriched GO Terms of Interacting Partners?
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