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DHX9 and HDLBP
Data Source:
HPRD
(in vitro)
DHX9
HDLBP
Description
DExH-box helicase 9
high density lipoprotein binding protein
Image
GO Annotations
Cellular Component
Intracellular Anatomical Structure
Nucleus
Nucleoplasm
Perichromatin Fibrils
Nucleolus
Cytoplasm
Centrosome
Cytosol
Polysome
Actin Cytoskeleton
Membrane
RISC Complex
Nuclear Body
Protein-containing Complex
Cytoplasmic Ribonucleoprotein Granule
Polysomal Ribosome
RISC-loading Complex
CRD-mediated MRNA Stability Complex
Nuclear Stress Granule
Ribonucleoprotein Complex
Nucleus
Cytoplasm
Cytosol
Polysome
Plasma Membrane
High-density Lipoprotein Particle
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Complex Binding
Regulatory Region RNA Binding
RNA Polymerase II Transcription Factor Binding
DNA Binding
DNA Helicase Activity
DNA Replication Origin Binding
Double-stranded DNA Binding
Single-stranded DNA Binding
Transcription Coregulator Activity
Transcription Coactivator Activity
RNA Binding
RNA Helicase Activity
Double-stranded RNA Binding
Single-stranded RNA Binding
MRNA Binding
Protein Binding
ATP Binding
ATPase Activity
Nucleoside-triphosphatase Activity
Chromatin DNA Binding
3'-5' DNA/RNA Helicase Activity
3'-5' RNA Helicase Activity
SiRNA Binding
RNA Stem-loop Binding
3'-5' DNA Helicase Activity
Triplex DNA Binding
Metal Ion Binding
Nucleoside-triphosphate Diphosphatase Activity
Importin-alpha Family Protein Binding
RNA Polymerase Binding
RISC Complex Binding
Polysome Binding
Single-stranded 3'-5' DNA Helicase Activity
Sequence-specific MRNA Binding
Promoter-specific Chromatin Binding
RNA Binding
MRNA Binding
Protein Binding
Lipid Binding
Cadherin Binding
Biological Process
Alternative MRNA Splicing, Via Spliceosome
MRNA Splicing, Via Spliceosome
Osteoblast Differentiation
DNA Replication
DNA-templated Transcription, Termination
Regulation Of Transcription By RNA Polymerase II
Inflammatory Response
RNA Secondary Structure Unwinding
Targeting Of MRNA For Destruction Involved In RNA Interference
Positive Regulation Of Type I Interferon Production
DNA Duplex Unwinding
Positive Regulation Of Interferon-alpha Production
Positive Regulation Of Interferon-beta Production
Positive Regulation Of Interleukin-18 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Tumor Necrosis Factor Production
Cellular Protein-containing Complex Assembly
DNA-templated Viral Transcription
G-quadruplex DNA Unwinding
Innate Immune Response
Positive Regulation Of Innate Immune Response
Positive Regulation Of DNA Repair
Positive Regulation Of DNA Replication
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of RNA Export From Nucleus
Positive Regulation Of Fibroblast Proliferation
Rhythmic Process
Positive Regulation Of Viral Transcription
Regulation Of MRNA Processing
Regulation Of Defense Response To Virus By Host
Positive Regulation Of Inflammatory Response
MRNA Transport
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Response To Cytokine Stimulus
Pyroptosis
Small RNA Loading Onto RISC
CRD-mediated MRNA Stabilization
Cellular Response To Tumor Necrosis Factor
Cellular Response To Exogenous DsRNA
Protein Localization To Cytoplasmic Stress Granule
Positive Regulation Of Viral Translation
Positive Regulation Of Polysome Binding
Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity
Positive Regulation Of Gene Silencing By MiRNA
Regulation Of Cytoplasmic Translation
Positive Regulation Of Cytoplasmic Translation
Lipid Transport
Cholesterol Metabolic Process
High-density Lipoprotein Particle Clearance
Pathways
RIP-mediated NFkB activation via ZBP1
DEx/H-box helicases activate type I IFN and inflammatory cytokines production
mRNA Splicing - Major Pathway
HDL clearance
Drugs
Diseases
GWAS
Apolipoprotein A1 levels (
32203549
)
Apolipoprotein B levels (
32203549
)
Fibrinogen levels (
28107422
26561523
)
HDL cholesterol levels (
32203549
)
Intraocular pressure (
29617998
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Prostate cancer (
23535732
)
Waist circumference adjusted for BMI (adjusted for smoking behaviour) (
28443625
)
Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) (
28443625
)
Waist circumference adjusted for BMI in non-smokers (
28443625
)
Interacting Genes
43 interacting genes:
ACTA1
AKAP8L
APBB1
BRCA1
DDX20
DDX5
DUX4
EIF2AK2
ESR1
GEMIN2
GEMIN4
GTF2B
H2AX
HDLBP
HNRNPC
HNRNPK
IL7R
ILF3
JUN
KHDRBS1
LINC01554
MBD2
NXF1
OGA
PCNA
POLR2A
PRMT1
PRPF40A
PRPF8
PTEN
RBM4
RELA
SMN1
SMN2
SNRPB
SNRPB2
SRPK1
SSRP1
STAU1
TBP
TOP2A
UBE2I
YWHAQ
13 interacting genes:
ADAR
CDC42
CSNK2A1
DHX9
ERBB2
ESR1
HMGB2
HSPB1
SMAD4
SOS1
SUMO2
TENT5A
XPOT
Entrez ID
1660
3069
HPRD ID
04386
00813
Ensembl ID
ENSG00000135829
ENSG00000115677
Uniprot IDs
B3KU66
Q08211
A0A024R4E5
B2R5V9
Q00341
PDB IDs
3LLM
3VYX
3VYY
1VIG
1VIH
2CTE
2CTF
2CTJ
2CTK
2CTL
2CTM
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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