DDX5 and HNRNPH3

Data Source:
BioGRID (two hybrid)

		DDX5	HNRNPH3
Description		DEAD-box helicase 5	heterogeneous nuclear ribonucleoprotein H3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane Extracellular Exosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex	Nucleus Nucleoplasm Spliceosomal Complex Ribonucleoprotein Complex
	Molecular Function	RNA Binding RNA Helicase Activity MRNA 3'-UTR Binding Protein Binding ATP Binding MH2 Domain Binding Pre-mRNA Binding Ribonucleoprotein Complex Binding SMAD Binding Androgen Receptor Binding R-SMAD Binding Primary MiRNA Binding Promoter-specific Chromatin Binding	RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Nuclear-transcribed MRNA Catabolic Process Epithelial To Mesenchymal Transition Regulation Of Transcription By RNA Polymerase II MRNA Transcription BMP Signaling Pathway Intracellular Estrogen Receptor Signaling Pathway Androgen Receptor Signaling Pathway Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Myoblast Differentiation Regulation Of Osteoblast Differentiation Rhythmic Process Regulation Of Androgen Receptor Signaling Pathway Pri-miRNA Transcription By RNA Polymerase II Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Pri-miRNA Transcription By RNA Polymerase II Positive Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA Regulation Of Skeletal Muscle Cell Differentiation	MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing Epithelial Cell Differentiation Regulation Of RNA Splicing
Pathways		SUMOylation of transcription cofactors mRNA Splicing - Major Pathway Estrogen-dependent gene expression Replication of the SARS-CoV-1 genome Replication of the SARS-CoV-2 genome
Drugs		Artenimol	Copper
Diseases		Prostate cancer
GWAS		Lung function (FVC) ( 30804560) Refractive error ( 32231278)
Interacting Genes		37 interacting genes: AKAP8 CALM1 CREBBP DDX17 DHX9 DUX4 EP300 ESR1 FBL FRS3 HNRNPA0 HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK IL7R KHDRBS1 MAPKAPK2 NCOA1 NCOA2 NCOA3 NDRG1 PIAS1 PIK3CA PIN1 PRKCA PSMA3 RBFOX2 RBM10 RBM4 SMAD3 SP1 SUMO2 TNNT1 TP53 UBE2I WBP11	100 interacting genes: ADORA2A ANXA11 CCL13 CHERP CRMP1 DDX17 DDX5 EEF1G ERG ERG28 HNRNPA0 HNRNPA1 HNRNPD HNRNPF HNRNPH1 HNRNPU HNRNPUL1 IL7R KAT5 MAPK6 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NCBP3 PIM2 RBM4 RPS4X SLC22A2 TTR UTP14A ZMYM2
Entrez ID		1655	3189
HPRD ID		01615	03818
Ensembl ID		ENSG00000108654	ENSG00000096746
Uniprot IDs		J3KTA4 P17844	A0A024QZK8 A0A024QZP1 B4DHY1 P31942 Q53F48
PDB IDs		3FE2 4A4D
Enriched GO Terms of Interacting Partners?
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