AP1G1 and AAGAB

Data Source:
BioGRID (two hybrid)

		AP1G1	AAGAB
Description		adaptor related protein complex 1 subunit gamma 1	alpha and gamma adaptin binding protein
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Cytosol Membrane AP-1 Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Recycling Endosome	Cytoplasm Cytosol Nuclear Speck
	Molecular Function	Protein Binding Kinesin Binding GTP-dependent Protein Binding Small GTPase Binding Clathrin Adaptor Activity Cargo Adaptor Activity	Protein Binding
	Biological Process	Intracellular Protein Transport Golgi To Vacuole Transport Receptor-mediated Endocytosis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Defense Response To Virus By Virus Golgi To Lysosome Transport	Protein Transport
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) HDL cholesterol levels ( 32203549) Post bronchodilator FEV1 ( 26634245) Refractive error ( 32231278) Superior temporal sulcus banks volume ( 31530798)	Allergic rhinitis ( 30013184) Asthma ( 31959851 31619474 29273806) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Bipolar disorder ( 31043756) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) FEV1 ( 30804560) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Proportion of activated microglia (midfrontal cortex) ( 30679421)
Interacting Genes		27 interacting genes: AAGAB AFTPH AP1AR AP1B1 AP1M2 AP1S1 AP1S2 ARF1 ARFRP1 BAALC CCDC91 CLINT1 CLTC DNER EPS15 HEATR5B KIF13A MAP1A PSEN2 RABEP1 RABGEF1 SNX9 SPTB SYNRG SYP UBL7 ZNF512B	9 interacting genes: AP1G1 AP1G2 AP1S3 AP2A1 AP2A2 AP2S1 EIF3C HEATR1 UNC119
Entrez ID		164	79719
HPRD ID		04637	07754
Ensembl ID		ENSG00000166747	ENSG00000103591
Uniprot IDs		A0A140VJE7 O43747 Q8IY97	Q6PD74
PDB IDs		1IU1
Enriched GO Terms of Interacting Partners?
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