DCK and MED19

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DCK	MED19
Description		deoxycytidine kinase	mediator complex subunit 19
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Cytosol	Mediator Complex
	Molecular Function	Deoxyadenosine Kinase Activity Deoxycytidine Kinase Activity Deoxyguanosine Kinase Activity ATP Binding Drug Binding Deoxynucleoside Kinase Activity Protein Homodimerization Activity	Transcription Coregulator Activity Protein Binding Transcription Factor Binding
	Biological Process	DAMP Biosynthetic Process Pyrimidine Nucleotide Metabolic Process Phosphorylation Pyrimidine Nucleoside Salvage Purine-containing Compound Salvage	Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Pyrimidine salvage Purine salvage	PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs		Fludarabine 2'-Deoxycytidine Elacytarabine
Diseases
GWAS		Pre-treatment viral load in HIV-1 infection ( 31219150)	Autism spectrum disorder or schizophrenia ( 28540026) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Neuroticism ( 29255261) Reticulocyte count ( 32888494) Schizophrenia ( 28991256 25056061 29483656)
Interacting Genes		5 interacting genes: DDX19B GOLM1 MED19 RXRG TFEC	19 interacting genes: APP DCK DHRS7B DTX2 GRB2 HLCS KANK2 MED17 MED27 MED31 MED8 MED9 MSX1 NEDD9 NFKBIA OSTF1 RADIL RIPPLY1 ZNF76
Entrez ID		1633	219541
HPRD ID		00507	17477
Ensembl ID		ENSG00000156136	ENSG00000156603
Uniprot IDs		F5CTF3 P27707	A0JLT2
PDB IDs		1P5Z 1P60 1P61 1P62 2A2Z 2A30 2A7Q 2NO0 2NO1 2NO6 2NO7 2NO9 2NOA 2QRN 2QRO 2ZI3 2ZI4 2ZI5 2ZI6 2ZI7 2ZI9 2ZIA 3HP1 3IPX 3IPY 3KFX 3MJR 3QEJ 3QEN 3QEO 4JLJ 4JLK 4JLM 4JLN 4KCG 4L5B 4Q18 4Q19 4Q1A 4Q1B 4Q1C 4Q1D 4Q1E 4Q1F 5MQJ 5MQL 5MQT
Enriched GO Terms of Interacting Partners?
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