AP2B1 and TGFBR2

  • Data Source:
  • HPRD (in vivo, two hybrid, in vitro)

AP2B1

TGFBR2

Description adaptor related protein complex 2 subunit beta 1 transforming growth factor beta receptor 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Breast cancer ( 29059683 23535729)
  • Cellular nuclear factor (erythroid-derived 2)-like 2 levels ( 30767168)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Estimated glomerular filtration rate ( 31152163)
  • Heel bone mineral density ( 30598549)
  • Metabolite levels ( 23823483)
  • Migraine ( 22683712 27322543)
  • Migraine - clinic-based ( 23793025)
  • Night sleep phenotypes ( 27126917)
  • Postprandial triglyceride response ( 32603185)
  • Response to chemotherapy in breast cancer hypertensive cases (cumulative dose) (bevacizumab) ( 25117820)
  • Systolic blood pressure ( 30224653)
  • Tonometry ( 17903302)
Interacting Genes 58 interacting genes: ACVR1 AFF4 AP1M1 AP1M2 AP2A2 AP2M1 AP2S1 APC ARRB1 ATM ATP23 ATP6V1G1 BUB1 BUB1B C2CD6 CCDC187 CLINT1 COL3A1 DHX58 DNAJC5 EGFR FMNL2 GPANK1 GTF2I HIP1 HSPB1 ITSN1 KANK2 KIAA0408 KPNA2 LDLRAP1 LONRF1 MEA1 MLH1 NECAP2 NEU4 NUP54 PIP5K1C POM121 PSORS1C2 RAPGEF3 RIBC2 SLC25A6 SLC2A8 SMAD4 SMURF1 SNAP91 TENT5C TERF2IP TEX12 TGFBR1 TGFBR2 THAP1 TUBGCP4 TXN2 U2AF1 U2AF1L5 UBC 50 interacting genes: ACVR1 ACVRL1 AP2B1 APP ARHGEF6 ARHGEF7 CCNB1 CCNB2 CD44 CDK1 CLU CTNNB1 DAB2 DAXX DYNLT4 EIF3I ENG FANCC GOPC KCNK18 MAP2K1 NRP1 OSR1 PAK1 PDGFRA PIK3R1 PIK3R2 PML PPP2CB PSMD14 RCVRN SMAD3 SMAD4 SMAD7 SNX6 STRAP TDGF1 TERT TGFB1 TGFB1I1 TGFB2 TGFB3 TGFBR1 TGFBR3 TGFBRAP1 TRAP1 TRMO TSSK1B ZFYVE9 ZNF510
Entrez ID 163 7048
HPRD ID 03015 01823
Ensembl ID ENSG00000006125 ENSG00000163513
Uniprot IDs A0A140VJE8 P63010 Q96EL6 A3QNQ0 D2JYI1 P37173
PDB IDs 1E42 2G30 2IV8 2IV9 2JKR 2JKT 2VGL 2XA7 4UQI 5M5R 6QH5 6QH6 6QH7 6URI 6YAE 6YAF 6YAH 6YAI 1KTZ 1M9Z 1PLO 2PJY 3KFD 4P7U 4XJJ 5E8V 5E8Y 5E91 5E92 5QIN 5TX4 5TY4
Enriched GO Terms of Interacting Partners?
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