AP2B1 and NOS2

  • Data Source:
  • BioGRID (affinity chromatography technology)

AP2B1

NOS2

Description adaptor related protein complex 2 subunit beta 1 nitric oxide synthase 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute anterior uveitis in ankylosing spondylitis ( 32492107)
  • Ankylosing spondylitis ( 23749187 30946743)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 23128233)
  • Cutaneous psoriasis ( 26626624)
  • Fractional exhaled nitric oxide (childhood) ( 24315451)
  • Inflammatory skin disease ( 25574825)
  • Psoriasis ( 25903422 20953189 23143594)
  • Psoriasis vulgaris ( 26626624)
  • Psoriatic arthritis ( 26626624)
Interacting Genes 58 interacting genes: ACVR1 AFF4 AP1M1 AP1M2 AP2A2 AP2M1 AP2S1 APC ARRB1 ATM ATP23 ATP6V1G1 BUB1 BUB1B C2CD6 CCDC187 CLINT1 COL3A1 DHX58 DNAJC5 EGFR FMNL2 GPANK1 GTF2I HIP1 HSPB1 ITSN1 KANK2 KIAA0408 KPNA2 LDLRAP1 LONRF1 MEA1 MLH1 NECAP2 NEU4 NUP54 PIP5K1C POM121 PSORS1C2 RAPGEF3 RIBC2 SLC25A6 SLC2A8 SMAD4 SMURF1 SNAP91 TENT5C TERF2IP TEX12 TGFBR1 TGFBR2 THAP1 TUBGCP4 TXN2 U2AF1 U2AF1L5 UBC 11 interacting genes: ACTB ACTN4 CAV1 PEX5 RAC1 RAC2 SLC9A3R1 SPSB1 SPSB2 SPSB4 SRC
Entrez ID 163 4843
HPRD ID 03015 01225
Ensembl ID ENSG00000006125 ENSG00000007171
Uniprot IDs A0A140VJE8 P63010 Q96EL6 P35228
PDB IDs 1E42 2G30 2IV8 2IV9 2JKR 2JKT 2VGL 2XA7 4UQI 5M5R 6QH5 6QH6 6QH7 6URI 6YAE 6YAF 6YAH 6YAI 1NSI 2LL6 2NSI 3E7G 3EJ8 3HR4 4CX7 4NOS 5TP6 5XN3 6JWM 6JWN 6KEY
Enriched GO Terms of Interacting Partners?
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