BRINP1 and SMPDL3A

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		BRINP1	SMPDL3A
Description		BMP/retinoic acid inducible neural specific 1	sphingomyelin phosphodiesterase acid like 3A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Dendrite Neuronal Cell Body	Extracellular Space Extracellular Exosome
	Molecular Function	Protein Binding	Sphingomyelin Phosphodiesterase Activity Protein Binding Phosphoric Diester Hydrolase Activity Zinc Ion Binding
	Biological Process	Behavioral Fear Response Cell Cycle Arrest Short-term Memory Cell Death Social Behavior Exploration Behavior Maternal Behavior Positive Regulation Of Neuron Differentiation Negative Regulation Of Cell Cycle Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Neurogenesis Cellular Response To Retinoic Acid Vocalization Behavior	Sphingomyelin Catabolic Process Nucleoside Triphosphate Catabolic Process
Pathways
Drugs
Diseases
GWAS		Change in LVEF in response to paclitaxel and trastuzumab in HER2+ breast cancer ( 28763429) Coffee consumption ( 31046077) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Hip circumference ( 28552196) Household income (MTAG) ( 31844048) Impulsivity (motor) ( 30718321) Manganese levels ( 26025379) Response to TNF inhibitor in rheumatoid arthritis (change in swollen 28-joint count) ( 30166627) Smoking status (ever vs never smokers) ( 30643258) Urinary sodium excretion ( 31409800)	Blood protein levels ( 30072576 29875488 28240269) Malaria ( 31844061)
Interacting Genes		5 interacting genes: CCND1 HDAC3 MDM2 RAC1 SMPDL3A	1 interacting genes: BRINP1
Entrez ID		1620	10924
HPRD ID		04181	10244
Ensembl ID		ENSG00000078725	ENSG00000172594
Uniprot IDs		O60477	Q92484
PDB IDs			5EBB 5EBE
Enriched GO Terms of Interacting Partners?
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