AP1B1 and ARF5

Data Source:
HPRD (in vivo, in vitro)

		AP1B1	ARF5
Description		adaptor related protein complex 1 subunit beta 1	ADP ribosylation factor 5
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GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Golgi Apparatus Cytosol Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle	Cytoplasm Golgi Apparatus Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding Protein Kinase Binding Clathrin Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Kidney Development Intracellular Protein Transport Determination Of Left/right Symmetry Heart Development Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Vesicle-mediated Transport
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Carotid atherosclerosis in HIV infection ( 20009918) Heel bone mineral density ( 30598549 28869591) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Pancreatic cancer ( 25086665) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Type 2 diabetes ( 23532257)
Interacting Genes		43 interacting genes: AGR3 AP1G1 AP1G2 AP1M2 ARF1 ARF5 ARF6 ARRB2 ATF7IP ATM ATR BARD1 BUB1 BUB1B CLTC CREBBP CRYBB1 FARS2 FMNL2 FNDC11 GPANK1 GTF2I KIF13A LDLRAP1 MLH1 MSGN1 MTNR1B MYG1 NECAP1 NTRK2 NUP54 PIP5K1C POM121 PRKDC PSORS1C2 RNF39 SHBG SLC2A8 SMAD2 TBC1D22B TSGA10IP U2AF1 U2AF1L5	14 interacting genes: ACY3 AP1B1 AP3B1 ARFIP1 ARFIP2 ASAP2 DTX3 ERBB2 GGA1 GORAB IKBKG PIP5K1A RAB11A RAB11FIP3
Entrez ID		162	381
HPRD ID		02541	00055
Ensembl ID		ENSG00000100280	ENSG00000004059
Uniprot IDs		Q10567	A4D0Z3 P84085
PDB IDs		4HMY 4P6Z 6CM9 6CRI 6D83 6D84 6DFF	2B6H
Enriched GO Terms of Interacting Partners?
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