SAXO1 and VPS28

Data Source:
BioGRID (two hybrid, two hybrid)

		SAXO1	VPS28
Description		stabilizer of axonemal microtubules 1	VPS28 subunit of ESCRT-I
Image		No pdb structure
GO Annotations	Cellular Component	Centriole Cytoskeleton Axonemal Microtubule Motile Cilium Ciliary Basal Body Sperm Flagellum	ESCRT I Complex Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Endosome Membrane Late Endosome Membrane Host Cell Extracellular Exosome
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding Ubiquitin Binding Protein-containing Complex Binding
	Biological Process	Cold Acclimation Cell Projection Organization Microtubule Anchoring Positive Regulation Of Cilium Assembly Protein Stabilization Cellular Response To Cold	Endosomal Transport Macroautophagy Viral Life Cycle Negative Regulation Of Protein Ubiquitination Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Protein Catabolic Process Intracellular Transport Of Virus Positive Regulation Of Ubiquitin-dependent Endocytosis
Pathways			Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS		Prudent dietary pattern ( 28644415)	Blood metabolite levels ( 26401656) Educational attainment ( 25201988)
Interacting Genes		48 interacting genes: ACTN2 AKAP8L ARMC7 BAG4 BEGAIN C19orf54 CARD9 CDKN2D CFAP206 CHERP CPNE7 CRK CYSRT1 FAM124A FBXO17 FHL2 FHL3 FHL5 GLYCTK HEXIM2 HOMER3 HSF2BP IQUB KIR3DX1 KLHL40 LMO1 LMO2 MAPK9 MVP NEK6 NUDT22 OIP5 OSGIN1 PFDN5 PLEKHG4 PM20D2 POLR1C SMARCB1 SORBS3 STK16 TNK1 TRIB3 TRIP6 VPS28 WWOX ZMAT1 ZMYND12 ZMYND19	45 interacting genes: ABI2 ASF1A BEX2 BLZF1 CARD9 CBX5 CCDC146 CDK18 CEP57L1 COX5B FABP3 GABARAP GEM GLCCI1 GOLGA2 INCA1 LMO3 MBIP NRDE2 NXF1 PDCD6IP PNMA5 PRKAA2 PRKAB2 RASSF5 SAXO1 SHC3 SKIL SMN1 SMN2 SUOX TCF12 TCF4 TRIM27 TRIM54 TSG101 TSNAX UBA52 UBC USHBP1 USP2 VPS37A VPS37B VPS37C VPS52
Entrez ID		158297	51160
HPRD ID		16676	11675
Ensembl ID		ENSG00000155875	ENSG00000160948
Uniprot IDs		B3KQ57 F6S232 Q5VZT6 Q8IYX7	A0A0S2Z5H5 Q548N1 Q9UK41
PDB IDs			6VME
Enriched GO Terms of Interacting Partners?
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