CYP2C19 and POR

CYP2C19

POR

Description cytochrome P450 family 2 subfamily C member 19 cytochrome p450 oxidoreductase
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acenocoumarol maintenance dosage ( 19578179)
  • Clopidogrel active metabolite levels ( 28207573)
  • Clozapine-to-N-desmethylclozapine metabolic ratio in schizophrenia ( 32555152)
  • Diastolic blood pressure ( 27841878 27618448)
  • Mean arterial pressure ( 27618448)
  • Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102)
  • Pulse pressure ( 27841878)
  • Response to clopidogrel therapy ( 28207573 19706858)
  • Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels) ( 24528284)
  • Serum metabolite levels ( 23093944)
  • Systolic blood pressure ( 27841878 30578418)
  • Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122)
  • Warfarin maintenance dose ( 23755828)
Interacting Genes 1 interacting genes: POR 15 interacting genes: CYB5A CYP17A1 CYP1A2 CYP2A6 CYP2C19 CYP2C9 CYP2D6 CYP2E1 CYP3A4 FANCC HMOX1 LINC01554 RABEPK STAT1 XRCC6
Entrez ID 1557 5447
HPRD ID 00486 00485
Ensembl ID ENSG00000165841 ENSG00000127948
Uniprot IDs P33261 P16435
PDB IDs 4GQS 1B1C 3FJO 3QE2 3QFC 3QFR 3QFS 3QFT 5EMN 5FA6
Enriched GO Terms of Interacting Partners?
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