IQUB and PKP3

Data Source:
BioGRID (two hybrid)

		IQUB	PKP3
Description		IQ motif and ubiquitin domain containing	plakophilin 3
Image			No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Motile Cilium	Cornified Envelope Nucleus Nucleoplasm Cytoplasm Plasma Membrane Cell-cell Junction Adherens Junction Cell Junction Desmosome Messenger Ribonucleoprotein Complex
	Molecular Function	Protein Binding	RNA Binding Protein Binding Enzyme Binding Translation Regulator Activity Alpha-catenin Binding Cadherin Binding Cell Adhesion Molecule Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Smoothened Signaling Pathway Cilium Assembly	Desmosome Assembly Regulation Of Translation Cell-cell Junction Assembly Positive Regulation Of Gene Expression Keratinization Cornification Protein Localization To Plasma Membrane Cell-cell Adhesion Negative Regulation Of MRNA Catabolic Process
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS			Anorectal malformation ( 31136621) Lymphocyte counts ( 32888494) Monocyte count ( 32888494)
Interacting Genes		57 interacting genes: ALX4 ANAPC11 ANKRD23 BHLHB9 BLZF1 CALCOCO2 CEP70 CEP76 CYSRT1 DIP2A DYNLL1 EYA2 FAM107A GOLGA2 IHO1 KATNAL1 KIFC3 KRT40 KRT75 KRT76 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-2 KRTAP12-4 LHX3 MAGEA6 MDFI PATZ1 PIH1D2 PIK3R3 PKP3 POU6F2 PRDM6 PRR23D1 PRR23D2 RHOH SAXO1 SMN1 SMN2 SORBS3 SYCE1 TMCC2 TP53BP2 TRAF2 TRAF6 TRIM23 TRIM27 TRIM42 TRIM50 TRIM54 TRIM55 TRIM63 ZNF143 ZNF410 ZNF526 ZRANB1	10 interacting genes: DSC1 DSC2 DSC3 DSG1 DSG2 DSG3 DSP IQUB JUP KRT18
Entrez ID		154865	11187
HPRD ID		08194	05711
Ensembl ID		ENSG00000164675	ENSG00000184363
Uniprot IDs		A0A024R771 Q8NA54	Q9Y446
PDB IDs		2DAF
Enriched GO Terms of Interacting Partners?
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